9月
Lenalidomide-4-aminomethyl；Lenalidomide-4-aminomethylLenalidomide-4-aminomethyl (2024/9/8)
簡(jiǎn)介：lenalidomide-4-aminomethyl is a crbn ligand derived from lenalidomide, which is utilized for the recruitment of crbn protein. by linking lenalidomide-4-aminomethyl to the ligand, a protac can be formed.
Bromchlorbuterol hydrochloride；Bromchlorbuterol hydrochlorideBromchlorbuterol hydrochloride (2024/9/8)
簡(jiǎn)介：bromchlorbuterol hydrochloride is a potent β-adrenergic agonist (β-agonist) compound commonly employed in the investigation of pulmonary conditions such as pulmonary disease and asthma.
低熔點(diǎn)錫鉍合金，錫基合金 (2024/9/8)
簡(jiǎn)介：低熔點(diǎn)錫鉍合金，巴氏合金，錫基合金錫鉍合金屬于環(huán)保型合金.在常溫下，呈固態(tài)、銀白色，熔點(diǎn)低為138度，固液體積收縮率為0.051%，具有較強(qiáng)的滲透性。錫鉍合金，是金屬中的一種，在我們平常的生活中比較常見(jiàn)。這種合金的熔點(diǎn)較別的合金比起來(lái)，熔點(diǎn)較低。它的里面包含了三種金屬，分別是銻，銅和鎘，其余的就是錫。
PEG2-Cl；PEG2-ClPEG2-Cl；PEG2-Cl (2024/9/8)
簡(jiǎn)介：peg2-cl is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Estrogen receptor modulator 6；Estrogen receptor modulator 6Estrogen receptor modulator 6 (2024/9/8)
簡(jiǎn)介：estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (er) β with a remarkable affinity (k i = 0.44 nm). this compound exhibits an impressive 19-fold selectivity for erβ over erα, as evidenced by its affinity (k i = 8.4 nm).
Bromo-C10-OBn；Bromo-C10-OBnBromo-C10-OBn；Bromo-C10-OBn (2024/9/8)
簡(jiǎn)介：bromo-c10-obn is a protac linker that can be used in the synthesis of protacs.
ADTL-SA1215；ADTL-SA1215ADTL-SA1215；ADTL-SA1215 (2024/9/8)
簡(jiǎn)介：adtl-sa1215 is a novel, highly selective small-molecule compound that acts as a specific activator of sirt3, a protein known to play a crucial role in modulating autophagy. this compound holds great potential in the treatment of triple-negative breast cancer, as it effectively targets the molecular pathways associated with this subtype of cancer.
Proprotogracillin；ProprotogracillinProprotogracillin (2024/9/8)
簡(jiǎn)介：proprotogracillin is a steroidal glycoside isolated from the bulbs of lilium speciosum.
FX1；化合物FX1FX1 (2024/9/8)
簡(jiǎn)介：fx1 is an effective and selective bcl6 inhibitor (ic50: 35 μm).
DMNB-caged-Serine；DMNB-caged-SerineDMNB-caged-Serine (2024/9/8)
簡(jiǎn)介：dmnb-caged-serine is a photocaged amino acid . dmnb is a caging group which is sensitive to blue light. dmnb-caged-serine can be incorporated into proteins in saccharomyces cerevisiae in response to the amber nonsense codon tag, which can be helpful for controlling the chemical composition of mammalian proteins..
3-Acetamidocoumarin；3-乙酰氨基香豆素3-Acetamidocoumarin (2024/9/8)
簡(jiǎn)介：3-acetamidocoumarin, a compound significant in biology and medicine, exhibits physiological effects and is utilized in treating various conditions, including burns, brucellosis-rheumatic diseases, and cancer.
N1,N12-Diacetylspermine dihydrochloride；N1,N12二乙酰精胺鹽酸鹽N1,N12-Diacetylspermine dihydrochloride|||Diac (2024/9/8)
簡(jiǎn)介：n1,n12-diacetylspermine dihydrochloride (diacetylspermine 2hcl) is a diacetylated derivative of spermine. the occurrence of cancer is associated with the up-regulation of n1,n12-diacetylspermine dihydrochloride, making it a biomarker to detect cancer occurrence.
OnzigolideOnzigolideBIM-23A760|||TBR-760|||Onzigolide (2024/9/8)
簡(jiǎn)介：onzigolide (bim-23a760), a chimeric compound combining properties of both dopamine and somatostatin, exhibits strong agonistic activity towards the d2 subtype of dopamine receptors (d2r) as well as type 2 somatostatin receptors (sstr2).
Fluoroglycofen；FluoroglycofenFluoroglycofen (2024/9/8)
簡(jiǎn)介：fluoroglycofen is a herbicide used in vineyards to eradicate weeds.
SKF 100398；SKF 100398d(CH2)5Tyr(Et)VAVP；d(CH2)5Tyr(Et)VAVP (2024/9/8)
簡(jiǎn)介：skf 100398, also known as d(ch2)5tyr(et)vavp, is a particular analog of arginine vasopressin (avp). it acts as a specific antagonist, specifically targeting the antidiuretic effect caused by both exogenous and endogenous avp.
N-Demethylansamitocin P-3；N-Demethylansamitocin P-3N-Demethylansamitocin P-3 (2024/9/8)
簡(jiǎn)介：n-demethylansamitocin p-3, a derivative of ansamitocin, an antitumor ansamycin antibiotic, can be synthesized through the action of streptomyces minutiscleroticus ifo 13361.
Hydroxy-PEG4-methyl acetate；Hydroxy-PEG4-methyl acetateHydroxy-PEG4-methyl acetate；Hydroxy-PEG4-meth (2024/9/8)
簡(jiǎn)介：hydroxy-peg4-methyl acetate is a peg-based linker compound utilized in protac synthesis.
(±)-Jasmonic acid(±)-Jasmonic acid(±)Jasmonic acid|||(±) Jasmonic acid (2024/9/8)
簡(jiǎn)介：(±)-jasmonic acid, a plant growth regulator and derivative of α-linolenic acid, exhibits chlorophyll-lowering effects in green and etiolated barley leaf segments, while also inhibiting the elongation of rice seedlings.
Thymoquinone；百里醌NSC 2228|||Thymoquinon；NSC 2228|||Thymoquinon|||百里醌 (2024/9/8)
簡(jiǎn)介：thymoquinone (nsc 2228) is a compound be found in herbs and spices with anti-inflammatory and anti-oxidant effects.
7-MAD-MDCPT；7-MAD-MDCPT7-MAD-MDCPT (2024/9/8)
簡(jiǎn)介：7-mad-mdcpt, a camptothecin analog, is a toxin payload in antibody drug conjugates (adcs).
Bombykol；蠶蛾醇Hexadeca-10E,12Z-dien-1-ol|||(10E,12Z)-hexadeca-10,12-dien-1-ol|||10E,12Z-hexadecadien-1 (2024/9/8)
簡(jiǎn)介：bombykol (isobombycol) is an insect sex pheromone that is produced as a sex attractant for the females of bombyx mori.
BMS-604992 free baseBMS-604992 free baseBMS-604992 free base|||EX-1314 free base (2024/9/8)
簡(jiǎn)介：bms-604992 (ex-1314) free base is a selective, orally active small-molecule growth hormone secretagogue receptor (ghsr) agonist. it exhibits high-affinity binding (k i = 2.3 nm) and potent functional activity (ec 50 = 0.4 nm). moreover, bms-604992 free base has the ability to stimulate food intake in rodents.
2-Nitrobenzaldehyde semicarbazone 13C,15N2；2-Nitrobenzaldehyde semicarbazone 13C,15N22-Nitrobenzalde (2024/9/8)
簡(jiǎn)介：2-nitrobenzaldehyde semicarbazone (13c, 15n2) is utilized in the lc-ms/ms method for semicarbazide analysis.
17-AEP-GA；17-AEP-GA17-AEP-GA (2024/9/8)
簡(jiǎn)介：17-aep-ga is a highly effective hsp90 antagonist compound that exhibits potent inhibition against the proliferation, survival, migration, and invasion of glioblastoma cells. additionally, it demonstrates adcs toxin activity.
Diclobutrazol；芐氯三唑醇Diclobutrazol (2024/9/8)
簡(jiǎn)介：diclobutrazol is a potent systemic fungicide effective against rusts, powdery mildews, and other fungal phytopathogens. it exhibits high activity in controlling various crop diseases, making it a valuable pesticide option.
Leukotriene E4；白三烯 E4LTE4；LTE4 (2024/9/8)
簡(jiǎn)介：leukotriene e4 (lte4) (lte4) is produced by the action of dipeptidyl peptidase on ltd4 and is a component of the slow reactive substance of anaphylaxis (srs-a).lte4 is present in plasma and urine and can be used to detect asthma.
S 38093 HCl；化合物S 38093 HClS 38093 HCl (2024/9/8)
簡(jiǎn)介：s 38093 is a novel brain-penetrant antagonist/inverse agonist of h3 receptors.
Moxonidine hydrochloride；鹽酸莫索尼定BDF5895hydrochloride；BDF5895hydrochloride|||鹽酸莫索尼定 (2024/9/8)
簡(jiǎn)介：moxonidine hydrochloride serves as a selective agonist for the imidazoline receptor subtype 1 and functions as an antihypertensive agent. it primarily acts within the central nervous system and demonstrates a significant preference for i1 imidazoline receptors over α2-adrenoceptors, with a 40-fold higher affinity. this compound effectively reduces stimulated norepinephrine overflow, indicating its potent efficacy. despite similar agents like agn192403 targeting the same receptor, moxonidine&acut
Tribromoacetonitrile；TribromoacetonitrileTribromoacetonitrile (2024/9/8)
簡(jiǎn)介：tribromoacetonitrile is a nitrogen-containing disinfection byproduct.
Simpinicline；化合物 SimpiniclineOC-02；OC-02 (2024/9/8)
簡(jiǎn)介：simpinicline (oc-02) (oc-02) is a highly selective nicotinic acetylcholine receptor (nachr) agonist that activates the trigeminal parasympathetic pathway and can be used to treat dry eye.
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