JPS014 TFA;化合物 JPS014 TFAJPS014 TFA (2024/9/14)
簡介:jps014 tfa, a benzamide-based von hippel-lindau (vhl) e3-ligase proteolysis targeting chimera (protac), effectively degrades class i histone deacetylase (hdac), particularly hdac1/2. this activity is associated with a higher number of differentially expressed genes and increased apoptosis in hct116 cells [1].
福建HONEYWELLQCS控制系統(tǒng)05406900高壓偏置板 (2024/9/14)
簡介:福建honeywellqcs控制系統(tǒng)05406900高壓偏置板伺服驅(qū)動維修
PROTAC BRD9 Degrader-4;化合物 PROTAC BRD9 Degrader-4PROTAC BRD9 Degrader-4 (2024/9/14)
簡介:protac brd9 degrader-4 is a bifunctional degrader targeting brd9, designed for cancer research applications.
Tri-GalNAc(OAc)3-Perfluorophenyl;化合物 Tri-GalNAc(OAc)3-PerfluorophenylTri-GalNAc(OAc)3-Perfluoropheny (2024/9/14)
簡介:tri-galnac(oac)3-perfluorophenyl is a pentafluorophenyl-modified triantenerrary n-acetylgalactosamine (tri-galnac) ligand utilized in the synthesis of galnac-lysosome-targeting chimeras (lytacs). these chimeras facilitate targeted protein degradation through engagement with the asialoglycoprotein receptor [1].
福建HONEYWELLQCS控制系統(tǒng)6580500046DAQ板 (2024/9/14)
簡介:福建honeywellqcs控制系統(tǒng)6580500046daq板電氣備件維修
PhosTAC7;化合物 PhosTAC7PhosTAC7 (2024/9/14)
簡介:phostac7, akin to protacs in promoting ternary complex formation, recruits a ser/thr phosphatase to a phosphosubstrate to facilitate dephosphorylation.
SJ995973;化合物 SJ995973SJ995973 (2024/9/14)
簡介:sj995973 (protac) represents a highly efficacious degrader of bromodomain and extra-terminal (bet) proteins.
福建HONEYWELLQCS控制系統(tǒng)6580801300CPU模組 (2024/9/14)
簡介:福建honeywellqcs控制系統(tǒng)6580801300cpu模組設(shè)備維修
PF15 TFA;化合物 PF15 TFAPF15 TFA (2024/9/14)
簡介:pf15 tfa, a protac targeting flt3 kinase and crbn, exhibits selective degradation of flt3-itd with a dc50 of 76.7 nm. the compound potently suppresses proliferation in flt3-itd-positive cells, reduces phosphorylation levels of flt3 and stat5, and demonstrates inhibition of tumor growth in murine leukemia models [1].
PROTAC IRAK3 degrade-1 formic;化合物 PROTAC IRAK3 degrade-1 formicPROTAC IRAK3 degrade-1 formic (2024/9/14)
簡介:protac irak3 degrade-1 (compound 23) is a selective and potent irak3 degrader, demonstrating an ic50 value of 5 nm [1].
Dovitinib-RIBOTAC TFA;化合物 Dovitinib-RIBOTAC TFADovitinib-RIBOTAC TFA (2024/9/14)
簡介:dovitinib ribotac tfa effectively and selectively cleaves pre-mir-21, functioning as a targeted rna degrader.
泉港區(qū)HONEYWELLQCS控制系統(tǒng)6580801390CPU板 (2024/9/14)
簡介:泉港區(qū)honeywellqcs控制系統(tǒng)6580801390cpu板伺服驅(qū)動維修
6-(4-Methoxyphenyl)-3-pyridazinamine;6-(4-甲氧苯基)噠嗪-3-胺6-(4-Methoxyphenyl)-3-pyridazinamine (2024/9/14)
簡介:6-(4-methoxyphenyl)-3-pyridazinamine is a gabaa receptor antagonist
Dovitinib-RIBOTAC;化合物 Dovitinib-RIBOTACDovitinib-RIBOTAC (2024/9/14)
簡介:dovitinib ribotac is a potent, selective targeted rna degrader that cleaves pre-mir-21.
南安縣HONEYWELLQCS控制系統(tǒng)05340900單側(cè)檢測部件 (2024/9/14)
簡介:南安縣honeywellqcs控制系統(tǒng)05340900單側(cè)檢測部件現(xiàn)場修
PROTAC PTK6 ligand-1;化合物 PROTAC PTK6 ligand-1PROTAC PTK6 ligand-1 (2024/9/14)
簡介:protac ptk6 ligand-1 serves as an intermediate in the synthesis of btk kinase inhibitors [1] and is utilized in the preparation of ard-61 [2].
Pomalidomide-6-OH;化合物 Pomalidomide-6-OHPomalidomide-6-OH (2024/9/14)
簡介:pomalidomide-6-oh, a pomalidomide-derived cereblon (crbn) ligand, facilitates the recruitment of crbn protein. this compound can be tethered to a protein ligand through a linker to create a proteolysis-targeting chimeric molecule (protac [1]).
政和縣HONEYWELLQCS控制系統(tǒng)47000006測厚儀頭溫傳感器 (2024/9/14)
簡介:政和縣honeywellqcs控制系統(tǒng)47000006測厚儀頭溫傳感器電氣備件維修
PROTAC KRAS G12C degrader-1;化合物 PROTAC KRAS G12C degrader-1PROTAC KRAS G12C degrader-1 (2024/9/14)
簡介:protac kras g12c degrader-1, a cereblon-based degrader, promotes crbn/kras g12c dimerization and facilitates the degradation of gfp-kras g12c in reporter cells [1].
DB-0646;化合物 DB-0646DB-0646 (2024/9/14)
簡介:db-0646 is a protac designed to induce the degradation of multiple kinases.
SB1-G-187;化合物 SB1-G-187SB1-G-187 (2024/9/14)
簡介:sb1-g-187 is a protac (proteolysis targeting chimera) that functions as a multi-kinase degrader [1].
永春縣HONEYWELLQCS控制系統(tǒng)6580700438銅安全螺栓 (2024/9/14)
簡介:永春縣honeywellqcs控制系統(tǒng)6580700438銅安全螺栓設(shè)備維修
BSJ-03-204 triTFA;化合物 BSJ-03-204 triTFABSJ-03-204 triTFA (2024/9/14)
簡介:bsj-03-204 tritfa is a potent and selective cereblon- and cdk-targeted protac (proteolysis targeting chimera) featuring palbociclib-based ligands for the degradation of cdk4/6. it exhibits ic50 values of 26.9 nm for cdk4/d1 and 10.4 nm for cdk6/d1, indicating strong inhibitory capabilities. notably, it spares ikzf1/3 from degradation and possesses anti-cancer activity [1].
HDAC6 degrader-1;化合物 HDAC6 degrader-1HDAC6 degrader-1 (2024/9/14)
簡介:hdac6 degrader-1, a proteolysis-targeting chimeric molecule (protac), incorporates the selective hdac6 inhibitor nexturastat a (nex a) for hdac6 binding, a linker, and an e3 ligase recruiting ligand. this compound effectively induces hdac6 degradation, displays superior selectivity over other hdac isoforms, and efficiently inhibits cell proliferation [1].
泉州HONEYWELLQCS控制系統(tǒng)05323900x射線接收電離室后的主板 (2024/9/14)
簡介:泉州honeywellqcs控制系統(tǒng)05323900x射線接收電離室后的主板伺服驅(qū)動維修
PROTAC BRD4 ligand-2 hydrochloride;化合物 PROTAC BRD4 ligand-2 hydrochloridePROTAC BRD4 ligand-2 hydroc (2024/9/14)
簡介:protac brd4 ligand-2 hydrochloride serves as a ligand targeting the brd4 protein, specifically designed for use with protac cft-2718.
ZXH-4-130 TFA;化合物 ZXH-4-130 TFAZXH-4-130 TFA (2024/9/14)
簡介:zxh-4-130 tfa is a hetero-protac (crbn-vhl compound) that efficaciously and selectively mediates the degradation of crbn. at a concentration of 10 nm in mm1.s cells, zxh-4-130 tfa achieves approximately 80% degradation of crbn [1].
永安縣HONEYWELLQCS控制系統(tǒng)05401100水份接收器底板 (2024/9/14)
簡介:永安縣honeywellqcs控制系統(tǒng)05401100水份接收器底板伺服驅(qū)動維修
Hispidin化合物Hispidin6-[(1E)-2-(3,4-二羥基苯基)乙烯基]-4-羥基-2H-吡喃-2-酮 (2024/9/14)
簡介:hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties
Thalidomide-4-O-C10-NH2 hydrochloride;化合物 Thalidomide-4-O-C10-NH2 hydrochlorideThalidomide-4-O-C10-N (2024/9/14)
簡介:thalidomide-4-o-c10-nh2 hydrochloride, a thalidomide-based cereblon ligand, facilitates the recruitment of the crbn protein. this compound can be conjugated with a protein ligand via a linker to synthesize protacs [1].