福清市HONEYWELLQCS控制系統(tǒng)05332600溫度檢測板 (2024/9/14)
簡介:福清市honeywellqcs控制系統(tǒng)05332600溫度檢測板設(shè)備維修
Thalidomide-O-C8-COOH;化合物 Thalidomide-O-C8-COOHThalidomide-O-C8-COOH (2024/9/14)
簡介:thalidomide-o-c8-cooh, also known as cereblon ligand 3, is a thalidomide-derived compound that serves as a cereblon (crbn) ligand for the targeted recruitment of crbn protein. it can be coupled via a linker to another ligand to create proteolysis-targeting chimeras (protacs)[1].
Thalidomide-4-O-C7-NH2 hydrochloride;化合物 Thalidomide-4-O-C7-NH2 hydrochlorideThalidomide-4-O-C7-NH2 (2024/9/14)
簡介:thalidomide-4-o-c7-nh2 hydrochloride, a thalidomide-based cereblon ligand, plays a role in the recruitment of crbn protein and, when linked to a protein ligand, forms protacs [1].
(S,R,S)-AHPC-Boc;化合物 (S,R,S)-AHPC-BocVH032-Boc;VH032-Boc (2024/9/14)
簡介:(s,r,s)-ahpc-boc (vh032-boc) serves as a ligand for the von hippel-lindau (vhl) protein recruitment in protac technology [1].
福州HONEYWELLQCS控制系統(tǒng)53000079加熱器 (2024/9/14)
簡介:福州honeywellqcs控制系統(tǒng)53000079加熱器伺服驅(qū)動維修
CCT367766 formic;化合物 CCT367766 formicCCT367766 formic (2024/9/14)
簡介:cct367766 formic is a potent third-generation heterobifunctional cereblon-based protein degradation probe (pdp, or protac) that selectively targets pirin for degradation, effectively diminishing its protein expression at low concentrations. this compound demonstrates moderate affinity towards the crbn-ddb1 complex, as denoted by an ic50 value of 490 nm, while exhibiting strong binding to recombinant pirin and crbn, with respective kd values of 55 nm and 120 nm. as such, cct367766 formic serves a
Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride;化合物 Amino-Tri-(carboxyethoxymethyl)-methane hy (2024/9/14)
簡介:amino-tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable peg-based linker employed in the synthesis of antibody-drug conjugates (adcs) and utilized as a peg-based protac linker for protacs synthesis, as documented in references [1] [2].
閩清縣HONEYWELLQCS控制系統(tǒng)05437400ECU板 (2024/9/14)
簡介:閩清縣honeywellqcs控制系統(tǒng)05437400ecu板設(shè)備維修
PZ703b TFA;化合物 PZ703b TFAPZ703b TFA (2024/9/14)
簡介:pz703b tfa, a bcl-xl protac degradation agent, promotes apoptosis and halts bladder cancer cell proliferation, making it a pertinent investigative compound for related oncological studies [1] [2].
Tz-Thalidomide;化合物 Tz-ThalidomideTz-Thalidomide (2024/9/14)
簡介:tz-thalidomide is a tetrazine-modified thalidomide (e3 ligase ligand) with some affinity for brd4.
德化縣HONEYWELL霍尼韋爾QCS系統(tǒng)8441102 (2024/9/14)
簡介:德化縣honeywell霍尼韋爾qcs系統(tǒng)8441102伺服驅(qū)動維修
Cantuzumab;化合物 CantuzumabCantuzumab (2024/9/14)
簡介:cantuzumab, a monoclonal antibody, binds to the canag antigen and is commonly conjugated with various cytotoxic agents to form antibody-drug conjugates (adcs), including cantuzumab mertansine and cantuzumab ravtansine [1].
Patritumab deruxtecan;化合物 Patritumab deruxtecanU3-1287|||HER3-DXd;U3-1287|||HER3-DXd (2024/9/14)
簡介:patritumab deruxtecan (her3-dxd), an antibody-drug conjugate (adc), comprises a fully human anti-her3 igg1 monoclonal antibody, patritumab, linked to a topoisomerase i inhibitor payload through a tetrapeptide-based cleavable linker, demonstrating anticancer activity [1].
閩清縣HONEYWELLQCS控制系統(tǒng)05439400傳感器通訊板 (2024/9/14)
簡介:閩清縣honeywellqcs控制系統(tǒng)05439400傳感器通訊板電氣備件維修
Iberdomide;化合物IberdomideCC-220;CC-220 (2024/9/14)
簡介:iberdomide (cc-220) is a modulator of cereblon( ic50 value of 60 nm in a competitive tr-fret assay).
Mirzotamab;化合物 MirzotamabMirzotamab (2024/9/14)
簡介:mirzotamab is an igg1κ antibody targeting cd276/b7-h3 and is the naked antibody to mirzotamab clezutoclax, consisting of 1320 amino acids.
福建HONEYWELLQCS控制系統(tǒng)08445201X射線高壓包 (2024/9/14)
簡介:福建honeywellqcs控制系統(tǒng)08445201x射線高壓包變頻器維修
Farletuzumab ecteribulin;化合物 Farletuzumab ecteribulinMORAb-202;MORAb-202 (2024/9/14)
簡介:farletuzumab ecteribulin (morab-202) is a highly cytotoxic antibody-drug conjugate (adc) targeting human folate receptor alpha (fra). this adc comprises the humanized farletuzumab antibody linked to mal-peg2-val-cit-pab-eribulin through reduced interchain disulfide bonds, with an agent-to-antibody ratio of 4.0. it demonstrates potent antitumor activity against fra-positive cells in vitro.
Tusamitamab ravtansine;化合物 Tusamitamab ravtansineHuMAb2-3-SPDB-DM4|||SAR-408701;HuMAb2-3-SPDB-DM4||| (2024/9/14)
簡介:tusamitamab ravtansine (sar-408701) is a dm4-linked anti-ceacam5 antibody-drug conjugate (adc) comprising a humanized monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule-5 (ceacam5) conjugated to a cytotoxic maytansinoid, selectively engaging ceacam5-positive tumor cells [1].
Briobacept;化合物 BriobaceptBR 3FC;BR 3FC (2024/9/14)
簡介:briobacept (br 3fc), a selective human monoclonal antibody, targets blys (baff) to induce b-cell apoptosis and is a recombinant glycoprotein comprising two blys receptor (br3) molecules fused to the fc domain of human igg1. it has applications in the study of rheumatoid arthritis (ra) [1] [2].
德化縣HONEYWELLQCS控制系統(tǒng)6542800036板子 (2024/9/14)
簡介:德化縣honeywellqcs控制系統(tǒng)6542800036板子設(shè)備維修
Vobramitamab;化合物 VobramitamabAEX-4089;AEX-4089 (2024/9/14)
簡介:vobramitamab, a humanized b7-h3 monoclonal antibody (mab), is conjugated to the prodrug seco-duba through a cleavable linker, creating the antibody-drug conjugate (adc) known as mgc018 [1].
Fomc-Gly-Gly-Phe-Gly-OH;化合物 Fomc-Gly-Gly-Phe-Gly-OHFomc-Gly-Gly-Phe-Gly-OH (2024/9/14)
簡介:compound d5 (fomc-gly-gly-phe-gly-oh) serves as a synthetic intermediate in the construction of an adc dual-drug-linker, and it is a crucial component for the assembly of this adc dual-drug linking unit [1].
南平HONEYWELLQCS控制系統(tǒng)6541600065LVDT位置反饋傳感器 (2024/9/14)
簡介:南平honeywellqcs控制系統(tǒng)6541600065lvdt位置反饋傳感器現(xiàn)場修
Belantamab mafodotin;化合物 Belantamab mafodotinBelantamab mafodotin-blm|||GSK2857916;Belantamab mafodo (2024/9/14)
簡介:belantamab mafodotin (gsk2857916) is a conjugate of a humanized, targeted monoclonal antibody directed against the b cell maturation antigen (bcma) and the cytotoxic agent mcmmaf, exhibiting anti-myeloma activity [1] [2].
Boc-Gly-Gly-Phe-Gly-OH TFA;化合物 Boc-Gly-Gly-Phe-Gly-OH TFABoc-Gly-Gly-Phe-Gly-OH TFA (2024/9/14)
簡介:boc-gly-gly-phe-gly-oh tfa, an n- and c-protected tetrapeptide, functions as a protease-cleavable linker in antibody-drug conjugates (adcs).
Ac-Exatecan;化合物 Ac-ExatecanAc-Exatecan (2024/9/14)
簡介:ac-exatecan, the acetylated form of exatecan (dx-8951), serves as a prevalent cytotoxic agent in antibody-drug conjugate (adc) formulations (adc cytotoxin) and acts as an inhibitor of dna topoisomerase i with an ic50 value of 2.2 μm [1].
沙縣HONEYWELLQCS控制系統(tǒng)05341600水份音叉驅(qū)動板 (2024/9/14)
簡介:沙縣honeywellqcs控制系統(tǒng)05341600水份音叉驅(qū)動板電氣備件維修
EGGGG-PEG8-amide-bis(deoxyglucitol);化合物 EGGGG-PEG8-amide-bis(deoxyglucitol)EGGGG-PEG8-amide-bis(deox (2024/9/14)
簡介:egggg-peg8-amide-bis(deoxyglucitol) constitutes a cleavable linker utilized in antibody-drug conjugates (adcs).
Bisindolylmaleimide V雙吲哚馬來酰亞胺雙吲哚馬來酰亞胺 V|||雙吲哚馬來酰亞胺 (2024/9/14)
簡介:bisindolylmaleimide v, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.