9月
Tannase；化合物 TannaseTannase (2024/9/14)
簡(jiǎn)介：tannase, also referred to as tanninyl hydrolase, is an enzyme adept at hydrolyzing ester and side bonds of tannic acid, thus liberating glucose and gallic acid. it plays a crucial role in clarifying wine and fruit juice [1].
Hemicellulase；化合物 HemicellulaseHemicellulase (2024/9/14)
簡(jiǎn)介：hemicellulase, a member of the glycoside hydrolase enzyme family, plays a pivotal role in the degradation of plant biomass and carbon flow in nature. it facilitates the breakdown of glucose and polymer bonds within plant fibers to water molecules, making it an essential tool in biochemical research [1].
α-Galactosidase；化合物 α-Galactosidaseα-Galactosidase (2024/9/14)
簡(jiǎn)介：α-galactosidase (ec 3.2.1.22), a glycoside hydrolase enzyme, is prevalent across animals, plants, and microorganisms, and is often utilized in biochemical research. it facilitates the hydrolysis of α-1,6-linked terminal galactose residues in substrates such as galactooligosaccharides, galactomannans, and galactolipids. this includes catalyzing key catabolic processes involved in the cleavage of glycoproteins, glycolipids, and polysaccharides [1].
Phosphodiesterase II；化合物 Phosphodiesterase IIPhosphodiesterase II (2024/9/14)
簡(jiǎn)介：phosphodiesterase 2 (ii), a key enzyme prominently involved in the hydrolysis of vital second messengers, cyclic adenosine monophosphate (camp) and cyclic guanosine monophosphate (cgmp), is frequently utilized in biochemical research. this enzyme is expressed across various tissues including the adrenal medulla, brain, heart, platelets, macrophages, and endothelial cells, playing a significant role in the regulation of diverse intracellular processes [1].
β-N-Acetylhexosaminidase；化合物 β-N-Acetylhexosaminidaseβ-N-Acetylhexosaminidase (2024/9/14)
簡(jiǎn)介：β-n-acetylhexosaminidase is an exoglycosidase that catalyzes the hydrolysis of terminal non-reducing β-n-acetylgalactosamine and glucosamine residues in oligosaccharides for epigenetic applications [1] .
Sarcosine oxidase；化合物 Sarcosine oxidaseSarcosine oxidase (2024/9/14)
簡(jiǎn)介：sarcosine oxidase (sao) catalyzes the oxidative demethylation of sarcosine, producing glycine, h2o2, and 5,10-ch2-tetrahydrofolate, substances commonly utilized in biochemical reactions [1].
Acetylcholinesterase；化合物 AcetylcholinesteraseAcetylcholinesterase (2024/9/14)
簡(jiǎn)介：acetylcholinesterase (ache; ec 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses, and is often used in biochemical research. acetylcholinesterase catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. acetylcholinesterase´s main role is to terminate neuronal transmission and signaling between synapses to prevent ach spread and activation of nea
Hemocyanin；化合物 HemocyaninHemocyanin (2024/9/14)
簡(jiǎn)介：hemocyanin, a substantial copper-bearing respiratory protein, serves as a crucial molecule in non-specific innate immune defense, exhibiting phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities [1].
Cholesterol oxidase；化合物 Cholesterol oxidaseCholesterol oxidase (2024/9/14)
簡(jiǎn)介：cholesterol oxidase (chox), a bacterial flavin oxidase containing fad utilized in biochemical research, catalyzes the oxidation of the c(3)-oh group of cholesterol (and other sterols) to cholest-5-en-3-one and subsequently isomerizes it to cholest-4-en-3-one [1].
Urocortin II, mouse；化合物 Urocortin II, mouseUrocortin II, mouse (2024/9/14)
簡(jiǎn)介：urocortin ii, mouse, is a selective and potent endogenous peptide agonist for the type-2 corticotropin-releasing factor (crf2) receptor, displaying k_i values of 0.66 nm for crfr2 and >100 nm for crfr1, signifying its high specificity. it engages crf2 receptors through mechanisms dependent on camp/pka and ca2+/camkii. additionally, urocortin ii, mouse is localized in specific regions of the central nervous system, influencing central neurons that process visceral sensory information and regulate
Dextranase；化合物 DextranaseDextranase (2024/9/14)
簡(jiǎn)介：dextranase, also known as glucan hydrolase, catalyzes the hydrolysis of α-(1,6)-glucosidic bonds in dextran. it is frequently utilized in biochemical research and has extensive applications in fields including food processing, sugar modification, and the preparation of agents. additionally, it serves a vital role in medicine by enhancing the activity of antibiotics for endocarditis [1].
Creatininase；肌酐酶CAH|||Creatinine amidohydrolase；CAH|||Creatinine amidohydrolase (2024/9/14)
簡(jiǎn)介：creatininase (cah) is a homohexameric enzyme found in pseudomonas putida, which can be used in the study of biosensors for creatinine assays and chronic renal failure.
Acyl coenzyme A synthetase；化合物 Acyl coenzyme A synthetaseAcyl coenzyme A synthetase (2024/9/14)
簡(jiǎn)介：acyl coenzyme a synthetase (acs), also known as acetyl coenzyme a synthetase, plays a pivotal role in biochemical research. this enzyme catalyzes the activation of fatty acids via coenzyme a through a two-step thioesterification process, resulting in the formation of acyl coenzyme a. subsequently, it is involved in numerous anabolic and catabolic lipid metabolism pathways and contributes to the tricarboxylic acid (tca) cycle during aerobic respiration [1].
Carboxylesterase；化合物 CarboxylesteraseCarboxylesterase (2024/9/14)
簡(jiǎn)介：carboxylesterases (cess), carboxylate hydrolases broadly distributed in nature and prevalent in mammalian liver, play a significant role in biochemical research. these enzymes facilitate the hydrolysis of diverse substrates, encompassing esters, thioesters, carbamates, and amides, resulting in the conversion of carboxylic acid esters into their respective alcohols and carboxylic acids [1].
Phosphoglycerate kinase；化合物 Phosphoglycerate kinasePhosphoglycerate kinase (2024/9/14)
簡(jiǎn)介：phosphoglycerate kinase (pgk) is a glycolytic enzyme that catalyzes the reversible transfer of phosphate groups from 1,3-bisphosphoglycerate (1,3-bpg) to adp, resulting in the production of 3-phosphoglycerate (3-pg) and atp. this enzyme not only plays a crucial role in the glycolysis pathway but also participates in gluconeogenesis by catalyzing the reverse reaction to produce 1,3-bpga and adp. phosphoglycerate kinase is essential for energy metabolism, nucleic acid interactions, tumor progressi
Phosphoglucomutase；磷酸葡萄糖變位酶Phosphoglucomutase (2024/9/14)
簡(jiǎn)介：phosphoglucomutase promotes cyst development in toxoplasma gondii. deficiency of phosphoglucomutase causes metabolic disorders.
Phospholipase D；化合物 Phospholipase DPhospholipase D (2024/9/14)
簡(jiǎn)介：phospholipase d (pld), an enzyme within the phospholipase superfamily, is prevalent across bacteria, yeast, plants, animals, and viruses, serving roles in biochemical research. it catalyzes the hydrolysis of glycerophospholipids´ phosphodiester bonds, generating phosphatidic acid and soluble choline. pld is implicated in numerous disease-related pathways, such as diabetes, atherogenesis, obesity, tumorigenesis, immune responses, and neuroendocrine functions [1].
ICA 110381；化合物ICA 110381ICA 110381 (2024/9/14)
簡(jiǎn)介：ica 110381 is a kcnq2/q3 potassium channel opener for the treatment of epilepsy
Rennin；化合物 RenninRennin (2024/9/14)
簡(jiǎn)介：rennin (chymosin) is a proteolytic enzyme related to pepsin, produced in the stomachs of certain animals, that effectively coagulates liquid milk into a semi-solid form, prolonging its retention in the stomach. it specifically targets k-casein, cleaving the peptide bond between the amino acid residues phenylalanine and methionine (105 and 106), and plays a crucial role in cheese production [1].
Malate dehydrogenase；化合物 Malate dehydrogenaseMalate dehydrogenase (2024/9/14)
簡(jiǎn)介：malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .
4-Phytase；化合物 4-Phytase4-Phytase (2024/9/14)
簡(jiǎn)介：4-phytase is a phosphohydrolase of inositol hexaphosphate [1] .
L-Lactate dehydrogenase；化合物 L-Lactate dehydrogenaseL-Lactate dehydrogenase (2024/9/14)
簡(jiǎn)介：l-lactate dehydrogenase, a redox enzyme, catalyzes the in vivo reduction of pyruvate to l-lactate with absolute enantiospecificity by utilizing nadh [1].
Pyruvate kinase；化合物 Pyruvate kinasePyruvate kinase (2024/9/14)
簡(jiǎn)介：pyruvate kinase is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and adp to pyruvate and atp [1] .
Diaphorase；化合物 DiaphoraseDiaphorase (2024/9/14)
簡(jiǎn)介：diaphorase, derived from anaerobic sludge organisms, catalyzes the denitrification biotransformation of hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) [1].
Creatine kinase (OcCK)；化合物 Creatine kinase (OcCK)Creatine kinase (OcCK) (2024/9/14)
簡(jiǎn)介：creatine kinase (occk) catalyzes the reversible reaction of creatine and atp to form phosphocreatine and adp. creatine kinase (occk) is a key enzyme for maintaining a constant atp/adp ratio during rapid energy turnover [1] .
Ribonuclease H；化合物 Ribonuclease HRibonuclease H (2024/9/14)
簡(jiǎn)介：ribonuclease h is an enzyme degrading the rna moiety of dna-rna hybrids [1] .
Hexokinase (ScHEX1)；化合物 Hexokinase (ScHEX1)Hexokinase (ScHEX1) (2024/9/14)
簡(jiǎn)介：hexokinase (schex1), a glycolytic enzyme, is inhibited by n-acetylglucosamine, which causes it to detach from the mitochondrial outer membrane. this detachment activates the nlrp3 inflammasome [1].
β-Glucosidase；化合物 β-Glucosidaseβ-Glucosidase (2024/9/14)
簡(jiǎn)介：β-glucosidase, a pivotal enzyme in cellulose degradation, belongs to the extensive family of glycoside hydrolases. it plays a crucial role in breaking down cellulose in soils and holds promise for assessing biological soil quality [1] [2] [3].
ODM-203；化合物ODM-203ODM-203 (2024/9/14)
簡(jiǎn)介：odm-203, a selective inhibitor of fgfr and vegfr, shows strong antitumor activity, and induces antitumor immunity
Nuclease S1；化合物 Nuclease S1Nuclease S1 (2024/9/14)
簡(jiǎn)介：nuclease s1, a specific endonuclease, degrades single-stranded dna (ssdna) and rna, and can remove protruding single-strand ends from double-stranded dna [1] [2].
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