9月
.@市場推送：SIEMENS羅賓康LDZ10501601可議價 (2024/9/14)
簡介：
SLC26A3-IN-3；化合物 SLC26A3-IN-3SLC26A3-IN-3 (2024/9/14)
簡介：slc26a3-in-3 (compound 4az), a potent slc26a3 inhibitor with an ic50 of 40 nm, is utilized for constipation and cystic fibrosis research [1].
.@市場推送：羅賓康LDZ10501432FUSE可議價 (2024/9/14)
簡介：
Sotuletinib dihydrochloride；化合物 Sotuletinib dihydrochlorideBLZ945 dihydrochloride；BLZ945 dihydrochlo (2024/9/14)
簡介：sotuletinib (blz945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting csf1-r with an ic50 of 1 nm. it promotes apoptosis in tumor cells and significantly restricts tumor growth in murine models, proving useful in cancer and amyotrophic lateral sclerosis (als) studies [1].
.@市場推送：西門子羅賓康A(chǔ)1A164877.00可議價 (2024/9/14)
簡介：
Chaetoglobosin C；化合物 Chaetoglobosin CChaetoglobosin C (2024/9/14)
簡介：chaetoglobosin c (compound 4), an anthraquinone-chromone derivative of chaetomium globosum kmitl-n0802, exhibits anti-tuberculosis activity [1].
.@市場推送：羅賓康A(chǔ)1A460A68.23M可議價 (2024/9/14)
簡介：
VU0029251；化合物 VU0029251VU0029251 (2024/9/14)
簡介：vu0029251 serves as a partial antagonist of mglur5, exhibiting a binding affinity with a k i of 1.07 μm. it also attenuates glutamate-induced calcium mobilization in hek293 cell membranes that express rat mglur5, demonstrating an ic 50 of 1.7 μm [1].
SM-324405；化合物SM 324405SM 324405；SM 324405 (2024/9/14)
簡介：sm-324405 is an agonist of tlr7.
.@市場推送：西門子羅賓康LDZ31500082.660可議價 (2024/9/14)
簡介：
CK2-IN-9；化合物 CK2-IN-9CK2-IN-9 (2024/9/14)
簡介：ck2-in-9, a potent and selective ck2 kinase inhibitor, exhibits an inhibitory concentration (ic50) of 3 nm against its target enzyme and hampers wnt reporter activity with an ic50 of 75 nm. in rats, it demonstrates low exposure (auc=0.36 μm/h) and high clearance (cl=65 ml/min/kg) [1].
.@市場推送：羅賓康LDZ10501925可議價 (2024/9/14)
簡介：
VK-1727；化合物 VK-1727VK-1727 (2024/9/14)
簡介：vk-1727, a selective small molecule inhibitor of ebna1, diminishes the dna binding activity of ebna1 and curtails the proliferation and metabolic activity of ebv+ cells while not affecting ebv- cells. this compound is utilized in research pertaining to multiple sclerosis [1].
.@市場推送：SIEMENS羅賓康A(chǔ)5E32539903可議價 (2024/9/14)
簡介：
RIPK2-IN-3；化合物 RIPK2-IN-3RIPK2-IN-3 (2024/9/14)
簡介：ripk2-in-3 (fcg806791773) is a receptor-interacting protein kinase 2 (ripk2) inhibitor with an ic50 value of 6.39 μm against recombinant truncated ripk2. it is applicable in the study of inflammation and cancer [1].
.@市場推送：西門子LDZ10501933電流互感器可議價 (2024/9/14)
簡介：
CAD031；化合物 CAD031CAD031 (2024/9/14)
簡介：cad031, a more active derivative of the alzheimer´s disease (ad) targeting agent j147, exhibits neuroprotective and memory-enhancing properties. it has been shown to enhance memory, improve dendritic structure, and stimulate cell division in the germinal zone of aged mice brains. additionally, cad031 demonstrates greater efficacy than j147 in human neural stem cell assays [1].
.@市場推送：西門子LDZ14501000.070功率單元可議價 (2024/9/14)
簡介：
.@市場推送：羅賓康A(chǔ)5E00116329可議價 (2024/9/14)
簡介：
(Z)-KC02；化合物 (Z)-KC02(Z)-KC02 (2024/9/14)
簡介：(z)-kc02 is an abhd16a inhibitor which targets the enzyme responsible for producing lysophosphatidylserine (lyso-ps), a lipid involved in regulating immune and neurological functions. this compound is linked to the mitigation of neurological disorders, including retinitis pigmentosa and cataracts (pharc), by depleting lyso-ps in lymphoblasts from affected individuals. moreover, (z)-kc02 diminishes lyso-ps levels and lipopolysaccharide-induced cytokine production in macrophages and influences lys
.@市場推送：西門子A1A363549.00電源板可議價 (2024/9/14)
簡介：
JP104；化合物 JP104JP104 (2024/9/14)
簡介：jp104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (faah) with a pic50 value of approximately 8 [1].
.@市場推送：羅賓康A(chǔ)5E02624585可議價 (2024/9/14)
簡介：
Diapocynin；化合物 DiapocyninDehydrodiacetovanillone；Dehydrodiacetovanillone (2024/9/14)
簡介：diapocynin (dehydrodiacetovanillone), a dimer of apocynin, acts as an orally administered inhibitor of nadph oxidase. it exhibits anti-inflammatory, neuroprotective, and antioxidant properties [1].
.@市場推送：西門子A1A363634.01可議價 (2024/9/14)
簡介：
Zoxamide；苯酰菌胺RH-7281；RH-7281 (2024/9/14)
簡介：zoxamide (rh-7281) is an oomycete-specific fungicide that impedes nuclear division in phytophthora capsici germlings and disrupts the microtubule cytoskeleton [1] [2].
.@市場推送：SIEMENS羅賓康A(chǔ)1A10000432.00M可議價 (2024/9/14)
簡介：
Dibenzylfluorescein；化合物 DibenzylfluoresceinDBF；DBF (2024/9/14)
簡介：dibenzylfluorescein (dbf), a fluorogenic probe (fluorescent dye), serves as a substrate for various cytochrome p450 (cyp) isoforms, such as cyp3a4, cyp2c8, cyp2c9, cyp2c19, and aromatase (cyp19). it is commonly utilized at its k_m value range of 0.87-1.9 μm (ex=485nm, em=535nm) to monitor alterations in cyp enzymatic activity attributable to pharmaceutical interventions or pathophysiological conditions [1] [2] [3] [4].
3-Isopropenyl-alpha,alpha-dimethylbenzyl；3-異丙基-二甲基芐基異氰酸酯TMI3-Isopropenyl-alpha,alpha-dimethylbenzyl (2024/9/14)
簡介：3-isopropenyl-alpha,alpha-dimethylbenzyl isocyanate is a bioactive chemical.
.@市場推送：羅賓康A(chǔ)5E31307047功率單元可議價 (2024/9/14)
簡介：
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