9月
Cetirizine Impurity D；西替利嗪雜質(zhì)DCetirizine Impurity D (2024/9/8)
簡介：cetirizine impurity d is an impurity of cetirizine. cetirizine is a second-generation antihistamine that acts as a specific, orally active, and long-acting antagonist of the histamine h1-receptor. cetirizine exhibits antiallergic properties and inhibits eosinophil chemotaxis in response to allergies.
ETC-159；化合物ETC159ETC159|||ETC-1922159|||ETC 159；ETC159|||ETC-1922159|||ETC 159 (2024/9/8)
簡介：etc-159 (etc-1922159) is a potent, orally available porcn inhibitor. it inhibits β-catenin reporter activity with an ic50 of 2.9 nm.
Bromodichloroacetaldehyde；一溴二氯乙醛Bromodichloroacetaldehyde (2024/9/8)
簡介：bromodichloroacetaldehyde belongs to the class of haloacetaldehydes, which are classified as disinfection byproducts (dbps) found in drinking water.
TfR-T12 acetate；化合物TfR-T12 acetateTfR-T12 acetate (344618-30-0 Free base)；TfR-T12 acetate (344618-30 (2024/9/8)
簡介：tfr-t12 acetate is a peptide binding to the transferrin receptor (tfr) and is subsequently internalized into tfr-expressing cells.
TfR-T12；TfR-T12TfR-T12；TfR-T12 (2024/9/8)
簡介：tfr-t12 is a transferrin receptor (tfr) binding peptide that can penetrate the blood-brain barrier (bbb), exhibiting a high binding affinity within the nanomolar (nm) range.
Enduracidin A；Enduracidin AEnduracidin A (2024/9/8)
簡介：enduracidin a, a primary constituent of the antibiotic compound enduracidin, is a polypeptide antibiotic manufactured by streptomyces fungicides.
9-cis-Vitamin A palmitate；9-cis-Vitamin A palmitate9-cis-Vitamin A palmitate|||9-cis-Retinyl palmita (2024/9/8)
簡介：9-cis-vitamin a palmitate (9-cis-retinyl palmitate) is a 9-cis isomer resulting from the interaction of vitamin a palmitate in corn flakes. it exhibits a biological activity of 26% compared to all-trans-vitamin a palmitate, which is known to be the most biologically active form of vitamin a.
L48H37；化合物L(fēng)48H37L48H37 (2024/9/8)
簡介：l48h37 is a chemically stable analog of curcumin. it exhibits potent inhibitory properties against myeloid differentiation protein 2 (md2), acting as a specific inhibitor. its mechanism involves inhibiting the interaction and signaling transduction of lps-tlr4/md2. l48h37 is primarily utilized in sepsis and lung injury research [1].
Enduracidin B；Enduracidin BEnduracidin B (2024/9/8)
簡介：enduracidin b, a polypeptide antibiotic, is a prominent constituent of enduracidin. this antibiotic is synthesized by streptomyces fungicides.
4,5-Dichlorocatechol；化合物4,5-Dichlorocatechol4,5-Dichlorocatechol (2024/9/8)
簡介：4,5-dichlorocatechol serves as a substrate for the broad-spectrum chlorocatechol 1,2-dioxygenase in pseudomonas chlororaphis rw71. its inhibition constant (ki) values for the dioxygenase enzyme are 30 nm with the chlorobenzoate-degrading strain pseudomonas putida ac27, and 4 nm for the dioxygenase in acidovorax sp. strain ps14.
Namoline；萘莫胺Namoline (2024/9/8)
簡介：namoline is a γ-pyrone compound that functions as a selective and reversible inhibitor of lysine-specific demethylase 1 (lsd1) with an ic50 of 51 μm in an hrp-coupled enzymatic assay. by impairing lsd1 demethylase activity, namoline effectively inhibits cell proliferation. due to its characteristics, namoline holds promise for research pertaining to androgen-dependent prostate cancer.
Talabostat mesylate；化合物Talabostat mesylateVal-boroPro|||PT100；Val-boroPro|||PT100 (2024/9/8)
簡介：talabostat mesylate (pt100) is an orally active, selective inhibitor of dipeptidyl peptidases iv (dpp4, ic50: 0.18 nm), including tumor-associated fibroblast activation protein. this agent may also stimulate the production of colony stimulating factors, such as granulocyte colony-stimulating factor (g-csf), resulting in the stimulation of hematopoiesis.
IRES-C11化合物IRES-C11IRES-C11 (2024/9/8)
簡介：ires-c11 is a specific inhibitor of translation that targets the internal ribosome entry site (ires) of the c-myc gene. it functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein a1, a trans-acting factor required for c-myc ires activity, and its corresponding ires. notably, ires-c11 does not inhibit the ires activity of bag-1, xiap, and p53.
Ethylhydrocupreine hydrochloride；乙氫去甲奎寧鹽酸鹽Optochin hydrochloride；Optochin hydrochloride|||乙氫去甲奎寧鹽酸鹽； (2024/9/8)
簡介：ethylhydrocupreine hydrochloride (optochin hydrochloride) is a derivative of quinine with antimicrobial activity against streptococcus pneumoniae.ethylhydrocupreine hydrochloride has antimalarial activity with an ic50 of 25.75 nm for plasmodium falciparum. ethylhydrocupreine hydrochloride has antimalarial activity with an ic50 of 25.75 nm against plasmodium falciparum.ethylhydrocupreine hydrochloride is an agonist of gallus gallus2 receptors (ggtas2r1, ggtas2r2 and ggtas2r7).
D-Dimannuronic acid；D-甘露糖醛酸二糖D-Dimannuronic acid (2024/9/8)
簡介：d-dimannuronic acid, derived from brown algae, is an alginate extract employed in the synthesis of sulfated polymannuronate (spmg)-derived oligosaccharides.
D-Panose；D-潘糖D-Panose (2024/9/8)
簡介：d-panose is a pan-type oligosaccharide derived from isomaltooligosaccharides (imos) and serves as a food ingredient.
SW157765；化合物 SW157765SW157765；SW157765 (2024/9/8)
簡介：sw157765 is a selective glucose transporter glut8 (slc2a8) inhibitor, a prodrug of many compounds, that selectively inhibits the uptake of fluorescent 2-deoxyglucose (2dg) in sw157765-sensitive cells in a dose-dependent manner, and can be used for the study of lung cancer.
BAD (103-127) (human) acetate；化合物BAD (103-127) (human) acetateBAD (103-127) (human) acetate (3317 (2024/9/8)
簡介：bad (103-127) (human) acetate is a 25-mer bad polypeptide from the bad bh3 domain that antagonizes the effects of bcl-xl.
德國菲尼克斯PHYNIX SURFIX SX-N1.5涂層測厚儀 (2024/9/8)
簡介：phynix surfix sx-n1.5涂層測厚儀
BAD (103-127) (human)；BAD (103-127) (human)BAD (103-127) (human) (2024/9/8)
簡介：bad (103-127) (human) is a 25-mer peptide obtained from the bh3 domain of bad. it effectively counteracts the activity of bcl-xl. notably, bad (103-127) (human) exhibits an approximately 800-fold greater binding affinity for bcl-xl compared to the 16-mer peptide.
ANATu00A0inhibitor-1；ANAT inhibitor-1ANATu00A0inhibitor-1 (2024/9/8)
簡介：anat inhibitor-1 serves as an inhibitor of human aspartate n-acetyltransferase (anat), targeting canavan disease.
德國菲尼克斯PHYNIX SURFIX SX-F1.5涂層測厚儀 (2024/9/8)
簡介：phynix surfix sx-f1.5涂層測厚儀
Maltoheptaose hydrate；麥芽七糖水合物Maltoheptaose hydrate (2024/9/8)
簡介：maltoheptaose hydrate, a maltooligosaccharide composed of seven glucose units, serves as an activator of phosphorylase b for the preparation of heptulose-2-phosphate.
Ziritaxestat；化合物GLPG1690GLPG1690；GLPG1690 (2024/9/8)
簡介：ziritaxestat (glpg1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.
Tau Peptide (275-305) (Repeat 2 domain)；Tau Peptide (275-305) (Repeat 2 domain)Tau Peptide (275-305) (2024/9/8)
簡介：tau peptide (275-305), also known as the r2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the alzheimer´s tau peptide. tau peptide (275-305) is considered crucial in determining the biochemical characteristics of the complete tau protein.
德國菲尼克斯PHYNIX SURFIX SX-FN1.5涂層測厚儀 (2024/9/8)
簡介：phynix surfix sx-fn1.5涂層測厚儀
N-Pivaloyl-L-tyrosine；N-Pivaloyl-L-tyrosineN-Pivaloyl-L-tyrosine (2024/9/8)
簡介：n-pivaloyl-l-tyrosine is an n-pivaloyl amino acid ester.
Histone H3 (5-23)；Histone H3 (5-23)Histone H3 (5-23)；Histone H3 (5-23) (2024/9/8)
簡介：histone h3 (5-23), a derivative of histone h3 consisting of amino acids 5-23, serves as a substrate for histone acetyltransferase (hat) assays.
Mal-PEG2-NHS；Mal-PEG2-NHSMal-PEG2-NHS；Mal-PEG2-NHS (2024/9/8)
簡介：mal-peg2-nhs is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
CH2COOH-PEG3-CH2COOHCH2COOH-PEG3-CH2COOHCH2COOH-PEG3-CH2COOH (2024/9/8)
簡介：ch2cooh-peg3-ch2cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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