9月
HJC0152 hydrochloride；化合物HJC0152 hydrochlorideHJC0152；HJC0152 (2024/9/8)
簡介：hjc0152 hydrochloride (hjc0152) is a signal transducer and activator of transcription 3 (stat3) inhibitor.
Cysteinylglycine acetate；半胱氨酸-甘氨酸醋酸鹽Cys-Gly Acetate|||Cysteinylglycine acetate（19246-18-5 Free base） (2024/9/8)
簡介：cysteinylglycine acetate (cys-gly acetate) is an acetate salt of cysteinylglycine. cysteinylglycine is an endogenous metabolite. cysteinylglycine is used in disease diagnosis.
Cysteinylglycine半胱氨酰甘氨酸半胱氨酰甘氨酸|||Cys-Gly (2024/9/8)
簡介：cysteinylglycine (cys-gly), is a biologically important compound since it is formed during the γ-glutamyl cycle. it is a l-cysteinyl peptide, that can be used in the studies of many peptides and important proteins.
VCMMAE；化合物VCMMAEmc-vc-PAB-MMAE；mc-vc-PAB-MMAE (2024/9/8)
簡介：vcmmae (mc-vc-pab-mmae) is a drug-linker conjugate for adc with potent antitumor activity.
MD2-IN-1；化合物MD2-IN-1inhibit|||MD2-IN-1|||Inhibitor|||MD2IN1|||Toll-like Receptor (TLR)|||MD-2-IN-1|| (2024/9/8)
簡介：md2-in-1 is a myeloid differentiation protein 2 (md2) inhibitor with a kd of 189 ?μm for the recombinant human md2 (rhmd2).
PF-3758309 hydrochloride；化合物PF-3758309 hydrochloridePF-03758309 hydrochloride；PF-03758309 hydrochlor (2024/9/8)
簡介：pf-3758309 hydrochloride (pf-03758309 hydrochloride) , is a pak4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (pak4) with potential antineoplastic activity. pf-3758309 hydrochloride binds to pak4, inhibiting pak4 activity and cancer cell growth. pak4, a serine/threonine kinase belonging to the p21-activated kinase (pak) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation
S1RA hydrochloride；化合物S1RA hydrochlorideE-52862 hydrochloride；4-[2-[[5-甲基-1-(2-萘基)-1H-吡唑-3-基]氧基]乙基]嗎 (2024/9/8)
簡介：s1ra hydrochloride (e-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1r, ki: 17 nm) antagonist, and has good selectivity against σ2r (ki > 1000 nm).
Nolatrexed；諾拉曲特Nolatrexed (2024/9/8)
簡介：nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.
SB1317 hydrochloride (1204918-72-8(free base))；化合物SB1317 hydrochlorideTG-02 hydrochloride；TG-02 hydr (2024/9/8)
簡介：sb1317 hydrochloride (1204918-72-8(free base)) (tg-02 hydrochloride) is an effective inhibitor of cdk2/jak2/flt3 (ic50: 13/73/56 nm).
Amenamevir；阿莫奈韋ASP2151；ASP2151|||阿莫奈韋 (2024/9/8)
簡介：amenamevir (asp2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (ec50: 14 ng/ml).
ML335；化合物ML335ML335 (2024/9/8)
簡介：ml335 is a selective activator of trek-1 and trek-2.
Mitapivat；化合物MitapivatPKR-IN-1；PKR-IN-1 (2024/9/8)
簡介：mitapivat (pkr-in-1), also known as pkm2 activator 1020 is a pkm2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.
KKL-10；化合物KKL10KKL 10；KKL 10 (2024/9/8)
簡介：kkl-10, a ribosome rescue inhibitor, has broad-spectrum antimicrobial activity against bacteria.
PF-06260933；化合物PF6260933PF-6260933|||PF 6260933|||PF6260933；PF-6260933|||PF 6260933|||PF6260933 (2024/9/8)
簡介：pf-06260933 is a highly selective small-molecule map4k4 inhibitor with ic50s of 3.7 and 160 nm for kinase and cell, respectively.
BQR-695；化合物BQR695BQR695|||NVP-BQR695；BQR695|||NVP-BQR695 (2024/9/8)
簡介：bqr-695 (nvp-bqr695) is a phosphatidylinositol 4-kinase (pi4k) inhibitor with ic50s of 80 and 3.5 nm for human pi4kiiiβ and plasmodium variant of pi4kiiiβ, respectively.
Autophinib；化合物AutophinibAutophinib (2024/9/8)
簡介：autophinib is a potent autophagy inhibitor with a novel chemotype with ic50 values of 90 and 40 nm for autophagy in starvation induced autophagy assay and rapamycin induced autophagy assay.
Broxaldine；溴沙定Brobenzoxaldine；Brobenzoxaldine|||溴沙定 (2024/9/8)
簡介：broxaldine (brobenzoxaldine) is a small molecular drug with antiprotozoal activity.
INF39；化合物INF39INF39 (2024/9/8)
簡介：inf39 is a noncytotoxic and irreversible nlrp3 inhibitor.
STAT5-IN-1；化合物STAT5 InhibitorSTAT5 Inhibitor；STAT5 Inhibitor (2024/9/8)
簡介：stat5-in-1 (stat5 inhibitor) is a cell-permeable inhibitor which suppresses stat5 via binding to the sh2 domain.
TCS-PIM-1-4a；5-[[3-(三氟甲基)苯基]亞甲基]-2,4-噻唑烷二酮SMI-4a；5-[[3-(三氟甲基)苯基]亞甲基]-2,4-噻唑烷二酮|||SMI-4a (2024/9/8)
簡介：tcs-pim-1-4a (smi-4a), a pim inhibitor, blocks mtorc1 activity through activation of ampk and kills a wide range of both myeloid and lymphoid cell lines (ic50=0.8-40 μm).
KDM4D-IN-1；化合物KDM4D-IN-1KDM4D-IN-1 (2024/9/8)
簡介：kdm4d-in-1 is a kdm4d inhibitor (ic50: 0.41±0.03 μm).
NCT-503；化合物NCT503NCT 503；NCT 503 (2024/9/8)
簡介：nct-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (phgdh), inhibiting serine synthesis from 3-phosphoglycerate in cells.
XMU-MP-1；化合物XMU-MP-1XMU-MP-1 (2024/9/8)
簡介：xmu-mp-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases mst1 and 2.
SAG hydrochloride (912545-86-9(free base))；化合物SAG hydrochlorideSmoothened Agonist HCl；Smoothened Ago (2024/9/8)
簡介：sag hydrochloride (912545-86-9(free base)) (smoothened agonist hcl) acts as an smo agonist.
SAR-20347；化合物SAR20347SAR20347；SAR20347 (2024/9/8)
簡介：sar-20347 is an inhibitor of tyk2, jak1/2/3 (ic50: 0.6/23/26/41 nm).
TAK-659 hydrochloride；化合物TAK-659 hydrochlorideTAK-659；TAK-659 (2024/9/8)
簡介：tak-659 hydrochloride (tak-659) is a potent and selective inhibitor of spleen tyrosine kinase (syk) with an ic50 value of 3.2 nm. it is selective against most other kinases, but potent toward both syk and flt3.
Targocil；化合物TargocilTargocil (2024/9/8)
簡介：targocil is used as a bacteriostatic inhibitor of wall teichoic acid (wta) biosynthesis which can inhibit the growth of methicillin-susceptible s. aureus (mssa) and methicillin-resistant s. aureus (mrsa) (mic90s: 2 μg/ ml) for both mrsa and mssa.
(S,R,S)-AHPC hydrochloride；化合物Protein degrader 1 hydrochlorideVHL Ligand 1 hydrochloride|||ULM-1|||P (2024/9/8)
簡介：(s,r,s)-ahpc hydrochloride (protein degrader 1 hydrochloride) is a building block in the synthesis of proteolysis-targeting chimera technologies (protacs).
E6446；化合物E6446E6446 (2024/9/8)
簡介：e6446 inhibits toll-like receptor (tlr)7 and 9 signaling. e6446 works in a variety of human and mouse cell types and inhibits dna-tlr9 interaction in vitro. when administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (cpg)-containing dna, which stimulates tlr9.
AG-494；化合物AG 494Tyrphostin AG-494|||AG 494|||Tyrphostin B48；Tyrphostin AG-494|||AG 494|||Tyrphostin (2024/9/8)
簡介：ag-494 (tyrphostin b48) is an inhibitor of epidermal growth factor receptor kinase.
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