Lipopolysaccharides, Escherichiacoli;脂多糖 來源于大腸桿菌Lipopolysaccharide, E. coli O111:B4;Lipopolysacchari (2024/9/8)
簡介:lipopolysaccharides, escherichiacoli (e. coli o111:b4) is a unique component of the cell wall of gram-negative bacteria, consisting of three regions: lipid a, oligosaccharide core and o-specific polysaccharide (o-antigen). lipopolysaccharides, escherichiacoli helps maintain the integrity of the outer cell membrane and protects bacteria from damage by bile salts and lipid antibiotics. lipopolysaccharides, escherichiacoli is a highly immunogenic antigen that can enhance immune responses and can be
Chloroacetamido-C-PEG3-C3-NHBoc;Chloroacetamido-C-PEG3-C3-NHBocChloroacetamido-C-PEG3-C3-NHBoc;Chlor (2024/9/8)
簡介:chloroacetamido-c-peg3-c3-nhboc is a polyethylene glycol (peg)-based linker utilized in the synthesis of proteolysis targeting chimeras (protacs).
MB-VC-MGBA;MB-VC-MGBAMB-VC-MGBA (2024/9/8)
簡介:mb-vc-mgba is a potent antitumor drug-linker conjugate for antibody-drug conjugates (adc), utilizing the minor-groove-binding dna-alkylating agent (mgba), connected through the adc linker mb-vc.
Pexopiprant;PexopiprantPexopiprant (2024/9/8)
簡介:pexopiprant, a potent oral antagonist of the prostaglandin d2 receptor 2 (dp2) with a k i value less than 100nm, is a valuable compound for asthma research.
Vitamin D3 octanoate;Vitamin D3 octanoateVitamin D3 octanoate;Vitamin D3 octanoate (2024/9/8)
簡介:vitamin d3 octanoate, an ester derived from vitamin d3, is commonly known as cholecalciferol. cholecalciferol is a naturally occurring form of vitamin d with notable properties such as inducing cell differentiation and impeding cancer cell proliferation.
NH2-PEG3 hydrochloride;NH2-PEG3 hydrochlorideNH2-PEG3 hydrochloride;NH2-PEG3 hydrochloride (2024/9/8)
簡介:nh2-peg3 hydrochloride is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
LP-184;LP-184LP-184 (2024/9/8)
簡介:lp-184 (compound 6), referred to as an acylfulvene analog, demonstrates the ability to inhibit tumor growth with noteworthy anti-cancer efficacy observed across multiple cell lines, including ovarian, colon, prostate, and pancreatic.
4-Pyridoxic Acid;4-吡哆酸Pyridoxic Acid|||4-Pyridoxinsaeure;4-吡哆酸|||Pyridoxic Acid|||4-Pyridoxinsaeure (2024/9/8)
簡介:4-pyridoxic acid (4-pyridoxinsaeure), a catabolite of vitamin b6, is a water-soluble b-group vitamin that can be used as a urinary diagnostic biomarker for determining the nutritional status of these vitamins.
CHO-C-PEG2-C-CHO;CHO-C-PEG2-C-CHOCHO-C-PEG2-C-CHO;CHO-C-PEG2-C-CHO (2024/9/8)
簡介:cho-c-peg2-c-cho is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
P53R3;化合物P53R3P53R3 (2024/9/8)
簡介:p53r3 is a potent reactivator of p53, effectively restoring sequence-specific dna binding to several p53 hot spot mutants, namely p53 r175h, p53 r248w, and p53 r273h. this compound exhibits p53-dependent antiproliferative effects with significantly higher specificity compared to prima-1 and promotes the recruitment of both wild-type p53 and p53 m237i to various target gene promoters. additionally, p53r3 markedly increases the mrna, total protein, and cell surface expression of death receptor 5 (
Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH;Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OHFmoc-Asn(Trt)-Ser(psi(Me,Me)p (2024/9/8)
簡介:fmoc-asn(trt)-ser(psi(me,me)pro)-oh is a dipeptide.
Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH;Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OHFmoc-Asp(OtBu)-Thr(psi(Me,M (2024/9/8)
簡介:fmoc-asp(otbu)-thr(psi(me,me)pro)-oh is a dipeptide.
Atrial natriuretic factor (1-28) (human, porcine);Atrial natriuretic factor (1-28) (human, porcine)A (2024/9/8)
簡介:atrial natriuretic factor (1-28) from both human and porcine sources is a powerful suppressor of pro-opiomelanocortin (pomc) mrna, while it only has a modest inhibition effect on βep-li release.
Benzyl-PEG2-CH2COOH;Benzyl-PEG2-CH2COOHBenzyl-PEG2-CH2COOH|||Benzyl-PEG2-CH2COOH|||Benzyl-PEG2-CH2CO (2024/9/8)
簡介:benzyl-peg2-ch2cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bromodichloronitromethane;BromodichloronitromethaneBromodichloronitromethane (2024/9/8)
簡介:bromodichloronitromethane is a halonitromethane compound, classified as a disinfection by-product (dbp) present in drinking water.
HXR9;HXR9HXR9 (2024/9/8)
簡介:hxr9 is a cell-permeable peptide that acts as a competitive antagonist of the hox/pbx interaction. it effectively inhibits the binding between hox proteins and the transcription factor pbx, specifically in paralogue groups 1 to 8. hxr9 selectively impairs cell proliferation and induces apoptosis in cells with a high expression of the hoxa/pbx3 genes, for instance, mll-rearranged leukemic cells.
Histone H3 (116-136), C116-136;Histone H3 (116-136), C116-136Histone H3 (116-136), C116-136;Histone (2024/9/8)
簡介:histone h3 (116-136), c116-136 is a peptide consisting of amino acids 116 to 136, which spans the c-terminus of histone h3.
AnsofaxineAnsofaxineAnsofaxine|||LPM570065freebase|||Toludesvenlafaxine|||LY03005freebase (2024/9/8)
簡介:ansofaxine, an snri compound, is commonly utilized in depression research as a serotonin-norepinephrine reuptake inhibitor.
MK-8617;化合物MK8617MK8617;MK8617 (2024/9/8)
簡介:mk-8617 is an orally available hif phd1 3 pan-inhibitor, inhibiting phd1/2/3 (ic50: 1.0/1.0/14 nm).
AFN-1252 tosylate;化合物 T4105LAPI-1252 tosylate;API-1252 tosylate (2024/9/8)
簡介:afn-1252 tosylate is an enoyl-acp reductase inhibitor.
Resolvin D3;Resolvin D3RvD3;RvD3 (2024/9/8)
簡介:resolvin d3 (rvd3) is a dysregulated mediator originating from docosahexaenoic acid (dha). it plays a crucial role in reducing arthritic inflammation.
Nelonemdaz potassiumNelonemdaz potassiumNeu2000potassium|||Salfaprodil (2024/9/8)
簡介:nelonemdaz potassium (also known as salfaprodil) is a potent nr2b-selective and uncompetitive antagonist of n-methyl-d-aspartate (nmda). this compound exhibits remarkable neuroprotection against cell death induced by both nmda and free radicals, in addition to its role as a free radical scavenger.
Benzyl-PEG2-acid;Benzyl-PEG2-acidBenzyl-PEG2-acid;Benzyl-PEG2-acid (2024/9/8)
簡介:benzyl-peg2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Phalloidin-TRITC;Phalloidin-TRITCPhalloidin-TRITC (2024/9/8)
簡介:phalloidin-tritc is a tritc labeled, red fluorescence probe for f-actin . phalloidin, bound to actin filaments, reacts covalently with amino acids glu-llt, met-ll9, and met355, which are very close to the nucleotide binding site.
Lafadofensine;LafadofensineLafadofensine (2024/9/8)
簡介:lafadofensine, a monoamine reuptake inhibitor, exhibits significant effects upon short-term administration.
γ-Glutamyl-S-allylcysteine;γ-谷氨酰胺-S-烯丙基半胱氨酸L-γ-Glutamyl-(S)-Allyl-Cysteine;L-γ-Glutamyl-(S)-Allyl-Cy (2024/9/8)
簡介:γ-glutamyl-s-allylcysteine (l-γ-glutamyl-(s)-allyl-cysteine) is a γ-glutamyl peptide extracted from allium sativum l. γ-glutamyl-s-allylcysteine possesses anti-glycation and antioxidant activities, and can inhibit the cholesterol biosynthesis.
Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH;Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OHFmoc-Lys(Boc)-Thr(psi(Me,Me)p (2024/9/8)
簡介:fmoc-lys(boc)-thr(psi(me,me)pro)-oh is a dipeptide.
24,25-Dihydrolanosterol;二氫羊毛甾醇Lanostenol;Lanostenol|||二氫羊毛甾醇 (2024/9/8)
簡介:24,25-dihydrolanosterol (lanostenol) is a chemical compound found in the seeds of the red pepper (capsicum annuum).
Chlorimuron-ethyl;Chlorimuron-ethylChlorimuron-ethyl (2024/9/8)
簡介:chlorimuron-ethyl, an influential herbicide extensively employed in soybean cultivation, exerts its action by inducing oxidative stress.
Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH;Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OHFmoc-Glu(OtBu)-Ser(psi(Me,M (2024/9/8)
簡介:fmoc-glu(otbu)-ser(psi(me,me)pro)-oh is a dipeptide.