9月
Blarcamesine hydrochloride；化合物Anavex 2-73Anavex 2-73|||AVex-73 hydrochloride|||AE-37 hydrochloride；A (2024/9/8)
簡(jiǎn)介：blarcamesine hydrochloride (avex-73 hydrochloride) is a sigma-1 receptor agonist (ic50: 860 nm).
Phytochelatin 2 (PC2)；Phytochelatin 2 (PC2)Phytochelatin 2 (PC2) (2024/9/8)
簡(jiǎn)介：phytochelatin 2, a short plant peptide, serves as an essential metal-binding compound. phytochelatins are a diverse group of plant compounds that play a crucial role in chelating metals, safeguarding against metal toxicity, and maintaining metal homeostasis.
Nor-Acetildenafil；Nor-AcetildenafilNor-Acetildenafil (2024/9/8)
簡(jiǎn)介：nor-acetildenafil is a derivative of acetildenafil, a synthetic phosphodiesterase inhibitor.
Kipukasin D；Kipukasin DKipukasin D (2024/9/8)
簡(jiǎn)介：kipukasin d is a naturally derived nucleoside with antibacterial properties, isolated from aspergillus versicolor.
Cefpodoxime proxetil impurity B；頭孢泊肟酯雜質(zhì)BCefpodoxime proxetil impurity B (2024/9/8)
簡(jiǎn)介：cefpodoxime proxetil impurity b is a constituent found in cefpodoxime proxetil, which is a third-generation cephalosporin. this compound, known as cefpodoxime proxetil, is a highly effective oral antibiotic with a broad spectrum of activity.
BSc3094；BSc3094BSc3094 (2024/9/8)
簡(jiǎn)介：bsc3094 is a potent tau aggregation inhibitor that demonstrates the potential for alzheimer´s disease (ad) research.
LY2409881；LY2409881LY2409881；LY2409881 (2024/9/8)
簡(jiǎn)介：ly2409881 is a selective iκb kinase β ( ikk2 ) inhibitor with an ic 50 of 30 nm.
Volasertib trihydrochloride伏拉塞替三鹽酸鹽BI6727trihydrochloride|||伏拉塞替三鹽酸鹽 (2024/9/8)
簡(jiǎn)介：volasertib (bi 6727) trihydrochloride is a dihydropteridinone derivative that exhibits potent and selective inhibition of polo-like kinase 1 (plk1), plk2, and plk3. it acts as an orally active atp-competitive inhibitor with an ic50 of 0.87 nm against plk1. additionally, volasertib trihydrochloride demonstrates ic50 values of 5 nm and 56 nm against plk2 and plk3, respectively. its mechanism of action includes inducing mitotic arrest and apoptosis. furthermore, volasertib trihydrochloride has been
Perivine；派利文堿Perivin；Perivin|||派利文堿 (2024/9/8)
簡(jiǎn)介：perivine (perivin) may resolve the instability of the retinoblastoma-associated proteins (rbap48) complex and thus be used in alzheimer´s disease therapy. perivine, vobasine, coronaridine and dichomine show hypotensive and muscle relaxant activity.
EGFR Protein Tyrosine Kinase Substrate；EGFR Protein Tyrosine Kinase SubstrateEGFR Protein Tyrosine K (2024/9/8)
簡(jiǎn)介：egfr protein tyrosine kinase substrate is a egfr protein tyrosine kinase substrate.
Tetrachloroveratrole；四氯藜蘆醚Tetrachloroveratrole (2024/9/8)
簡(jiǎn)介：tetrachloroveratrole, a byproduct of bacterial o-methylation, arises from the biodegradation of tri- and tetra chloroguaiacols. these chloroguaiacols emerge as a result of the wood pulp bleaching process within the paper manufacturing industry.
Propargyl-PEG2-CH2COOH；Propargyl-PEG2-CH2COOHPropargyl PEG2 CH2COOH|||Propargyl-PEG2-CH2COOH|||Propa (2024/9/8)
簡(jiǎn)介：propargyl-peg2-ch2cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propynyl-PEG1-Ac；Propynyl-PEG1-AcPropynyl-PEG1-Ac；Propynyl-PEG1-Ac (2024/9/8)
簡(jiǎn)介：propynyl-peg1-ac is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
(E)-3-(4-Methoxyphenyl)acrylic acid(E)-3-(4-甲氧基苯基)丙烯酸(E)-3-(4-甲氧基苯基)丙烯酸 (2024/9/8)
簡(jiǎn)介：(e)-3-(4-methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of etlingera pavieana (pierre ex gagnep.) r. m. sm. it is a novel α-glucosidase inhibitor. (e)-3-(4-methoxyphenyl)acrylic acid has hepatoprotective activity, antiamnesic activity, enhances cognitive effects, and can be used to lower blood pressure sugar.
Wnt/β-catenin agonist 2；Wnt/β-連環(huán)蛋白激動(dòng)劑2Wnt/β-catenin agonist 2 (2024/9/8)
簡(jiǎn)介：wnt/β-catenin agonist 2 activates wnt/β-catenin signaling and is an effective wnt agonist. wnt/β-catenin agonist 2 can be used in the study of diseases related to signal transduction and is closely related to cancer invasion and metastasis.
4-Amino-L-phenylalanine；4-Amino-L-phenylalanine4-Amino-L-phenylalanine (2024/9/8)
簡(jiǎn)介：4-amino-l-phenylalanine is an endogenous metabolite.
7,15-Dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid；7,15-Dihydroxy-4,4,14-trimethyl-3,11 (2024/9/8)
簡(jiǎn)介：7,15-dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid is a ganoderma triterpenoid found in ganoderma lucidum karst. this compound is acknowledged as a significant bioactive ingredient. it can be employed in the investigation of different etiologies.
JTS-653；JTS-653JTS-653 (2024/9/8)
簡(jiǎn)介：jts-653 is a potent and selective in vitro and in vivo antagonist of transient receptor potential vanilloid 1 (trpv1). it effectively attenuates chronic pain resistant to non-steroidal anti-inflammatory drugs.
L-Azidohomoalanine hydrochloride；L-疊氮高丙氨酸鹽酸鹽H-L-Aha-OH hydrochloride；H-L-Aha-OH hydrochloride (2024/9/8)
簡(jiǎn)介：l-azidohomoalanine hydrochloride (h-l-aha-oh hydrochloride) is an alkyl chain-based protac linker.
L-Homopropargylglycine hydrochloride；L-Homopropargylglycine hydrochlorideL-Homopropargylglycine hydr (2024/9/8)
簡(jiǎn)介：l-homopropargylglycine hydrochloride is an alkyl-based protac linker used in protac synthesis. it is an amino acid analog of methionine with an alkyne group, enabling a click chemical reaction with azide-containing alexa fluor.
Diadenosine pentaphosphate pentalithium；Diadenosine pentaphosphate pentalithiumDiadenosine pentaphos (2024/9/8)
簡(jiǎn)介：diadenosine pentaphosphate pentalithium is an endogenous vasoactive purine dinucleotide, isolated from thrombocytes. it is a member of the diadenosine polyphosphates (apna, n=2–7) and is found in secretory vesicles of platelets, chromaffin cells, torpedo synaptic terminals, and brain synaptosomes.
Penetratin；PenetratinPenetratin (2024/9/8)
簡(jiǎn)介：penetratin is a peptide derived from the amphiphilic drosophila antennapedia homeodomain.
IDR-1；IDR-1IDR-1 (2024/9/8)
簡(jiǎn)介：idr-1 is an antimicrobial peptide with activity against both gram-positive and gram-negative bacteria. this compound modulates innate immunity to counter infections while avoiding evident toxicities. additionally, idr-1 exhibits anti-inflammatory and anti-infective properties, increases the levels of monocyte chemokines, and reduces the release of pro-inflammatory cytokines.
UK122UK122UK122 (2024/9/8)
簡(jiǎn)介：uk122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (upa) with an ic50 value of 0.2 μm. it displays negligible to minimal inhibition towards tissue-type plasminogen activator (tpa), plasmin, thrombin, and trypsin (all ic50 >100 μm). functioning as a 4-oxazolidinone analogue, uk122 is an anticancer agent that effectively inhibits cancer cell migration and invasion.
MDM2-IN-21MDM2-IN-21MDM2-IN-21 (2024/9/8)
簡(jiǎn)介：mdm2-in-21 is a potent mdm2 inhibitor. mdm2-in-21 can be used for the research of cancer.
pNP-ADPr；pNP-ADPrpNP-ADPr|||ADP-ribose-pNP；pNP-ADPr|||ADP-ribose-pNP (2024/9/8)
簡(jiǎn)介：pnp-adpr is a colorimetric substrate employed in the first continuous activity assays for poly(adp-ribose) glycohydrolase (parg) and adp-ribosyl hydrolase 3 (arh3). its utilization facilitates research on poly(adp-ribose) polymerase (parp) enzymes.
Pyrazosulfuron-ethyl；Pyrazosulfuron-ethylPyrazosulfuron-ethyl (2024/9/8)
簡(jiǎn)介：pyrazosulfuron-ethyl, a sulphonylurea herbicide belonging to the acetolactate synthase inhibiting category, has gained extensive application in the suppression of weed proliferation within commercial cereal, soybean, and vegetable fields.
Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH；Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OHFmoc-Trp(Boc)-Thr(psi(Me,Me)p (2024/9/8)
簡(jiǎn)介：fmoc-trp(boc)-thr(psi(me,me)pro)-oh is a dipeptide.
3-TYP；化合物3-TYP3-(1H-1,2,3-triazol-4-yl) pyridine；3-(1H-1,2,3-triazol-4-yl) pyridine (2024/9/8)
簡(jiǎn)介：3-typ (3-(1h-1,2,3-triazol-4-yl) pyridine) is a selective sirt3 inhibitor.
MMP13-IN-2；MMP13-IN-2MMP13-IN-2；MMP13-IN-2 (2024/9/8)
簡(jiǎn)介：mmp13-in-2 is a highly potent, selective, and orally active inhibitor of mmp-13. it demonstrates exceptional potency against mmp-13, with an ic50 value of 0.036 nm, and exhibits selectivities greater than 1,500-fold over mmp-1, 3, 7, 8, 9, 14, and tace. moreover, mmp13-in-2 possesses the capability to effectively inhibit collagen release from cartilage in vitro. consequently, mmp13-in-2 holds great potential for advancing research on collagenase-related diseases.
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