9月
Goserelin acetate；醋酸戈舍瑞林Fertilan|||ICI-118630 acetate|||Zoladex；醋酸戈舍瑞林|||Fertilan|||ICI-118630 aceta (2024/9/8)
簡介：goserelin acetate (fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
Histone H1-derived Peptide；Histone H1-derived PeptideHistone H1-derived Peptide；Histone H1-derived P (2024/9/8)
簡介：histone h1-derived peptide is a phosphopeptide with peptide substrates that consist of a sequence aligned with the optimal recognition motif for cyclin-dependent kinases (cdks).
Epigambogic acid；表藤黃酸Epigambogic acid (2024/9/8)
簡介：epigambogic acid is a small molecule compound from garcinia cambogia with anti-tumor, antitussive, expectorant and anti-inflammatory activities.
Vercirnon sodium維塞諾鈉鹽GSK-1605786 sodium|||CCX282-Bsodium|||維塞諾鈉鹽|||Traficet-ENsodium (2024/9/8)
簡介：vercirnon (gsk1605786a) sodium is an orally bioavailable, selective, and potent ccr9 antagonist. it effectively inhibits ccr9-mediated calcium mobilization and chemotaxis in molt-4 cells, exhibiting ic50 values of 5.4 nm and 3.4 nm, respectively. demonstrating high selectivity, vercirnon sodium does not significantly affect ccr1-12 or cx3cr1-7, with ic50 values exceeding 10 μm for these receptors. additionally, it inhibits ccl25-directed chemotaxis equally well in both ccr9 splice variants, ccr9
Larsucosterol；LarsucosterolDUR-928；DUR-928 (2024/9/8)
簡介：larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.
MLS1082；MLS1082MLS1082 (2024/9/8)
簡介：mls1082 is a pyrimidone-derived compound that acts as a positive allosteric modulator of d1-like dopamine receptors. it exhibits an ec 50 value of 123 nm for stimulating g protein signaling in response to dopamine activation.
Ganciclovir mono-O-acetate；Ganciclovir mono-O-acetateGanciclovir mono-O-acetate (2024/9/8)
簡介：ganciclovir mono-o-acetate is a derivative of ganciclovir, an orally active antiviral agent with activity against cmv. it belongs to the group of nucleoside analogues.
Mad1 (6-21)；Mad1 (6-21)Mad1 (6-21)；Mad1 (6-21) (2024/9/8)
簡介：mad1 (6-21) is a peptide fragment derived from the mad1 protein, specifically encompassing residues 6 to 21. this fragment exhibits binding affinity towards the mammalian sin3a pah2 domain, with a kd value of approximately 29 nm.
Azido-PEG6-CH2COOH；Azido-PEG6-CH2COOHAzido-PEG6-CH2COOH；Azido-PEG6-CH2COOH (2024/9/8)
簡介：azido-peg6-ch2cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Maleimide-C10-NHS esterMaleimide-C10-NHS esterMaleimide-C10-NHS ester (2024/9/8)
簡介：maleimide-c10-nhs ester is an alkyl/ether-based linker for protac synthesis.
SC-560；化合物SC560SC560；SC560 (2024/9/8)
簡介：sc-560 is a member of the diaryl heterocycle class of cyclooxygenase (cox) inhibitors.
Fmoc-Tyr(tBu)-Ser(psi(Me,Me)pro)-OH；Fmoc-Tyr(tBu)-Ser(psi(Me,Me)pro)-OHFmoc-Tyr(tBu)-Ser(psi(Me,Me)p (2024/9/8)
簡介：fmoc-tyr(tbu)-ser(psi(me,me)pro)-oh is a dipeptide.
BODIPY-Cholesterol；化合物BODIPY-CholesterolBCh2；BCh2 (2024/9/8)
簡介：bodipy-cholesterol (tf-chol) is a cholesterol analog with a fluorescent bodipy motif and cellular permeability, and is a novel bodipy cholesterol probe.bodipy-cholesterol can be used to study intracellular sterol uptake and interorganelle sterol flux.
TFAX 568, SE；TFAX 568, SETFAX 568, SE (2024/9/8)
簡介：tfax 568, se is an orange fluorescent dye with a wide ph-insensitive range of 4-10. it efficiently forms highly luminous and photostable conjugates with proteins or antibodies, specifically goat anti-mouse igg.
TFAX 488,TFP；TFAX 488,TFPTFAX 488,TFP (2024/9/8)
簡介：tfax 488,tfp is a green fluorescent dye that demonstrates ph-insensitivity across an extensive range (ph 4-10). it provides highly intense and long-lasting conjugates with proteins or antibodies, such as goat anti-mouse igg and streptavidin.
PA-8；化合物PA-8PA-8 (2024/9/8)
簡介：pa-8 is a small molecule receptor antagonist for pacap type i (pac1) that is selective, effective, and orally active. pa-8 inhibits pacap-induced creb phosphorylation at pac1- receptors, but does not inhibit vpac1- or vpac2 receptors. pa-8 also inhibited pacap-induced elevation of camp levels in vitro (ic50 = 2 nm) and pacap-induced aversive response and mechanical atopic pain after intrathecal injection in vivo.
Coumberone；CoumberoneCoumberone (2024/9/8)
簡介：coumberone is a metabolic fluorogenic probe and isoform-selective substrate for all akr1c isoforms. it can be reduced by all four members of the akr1c family to its fluorescent alcohol coumberol. coumberone is a valuable tool for researching akr1c.
KG5；化合物KG5KG5 (2024/9/8)
簡介：kg5 is a dual allosteric inhibitor of pdgfrβ and b-raf with a kd of 520 nm and 300 nm for pdgfrβ and pdgfrα. kg5 inhibits flt3, kit, and c-raf with anticancer and antiangiogenic activities.
HCVP-IN-1；HCVP-IN-1HCVP-IN-1 (2024/9/8)
簡介：hcvp-in-1 (compound 1) is a hepatitis c viral polymerase (hcvp) inhibitor.
L-Lactic acid-13C3；L-Lactic acid-13C3L-Lactic acid-13C3|||(S)-2-hydroxypropanoic-13-C3；L-Lactic acid (2024/9/8)
簡介：l-lactic acid-13c3 is a stable isotope labeled l-lactic acid analog. l-lactic acid-13c3 can be used for lactate metabolism research.
N-trifluoroacetyl-β-alanyl chloride；N-trifluoroacetyl-β-alanyl chlorideN-trifluoroacetyl-β-alanyl ch (2024/9/8)
簡介：n-trifluoroacetyl-β-alanyl chloride is a cleavable linker utilized in the synthesis of antibody-drug conjugates (adcs), which are bioconjugates formed by attaching drug molecules to antibodies.
AS8351；化合物AS8351NSC51355|||AS-8351|||AS 8351；NSC51355|||AS-8351|||AS 8351 (2024/9/8)
簡介：as8351 (nsc51355) is a histone demethylase inhibitor. it has been used in combination with chir99021, a 83-01, bix01294, sc-1, y-27632, oac2, su 16f, and jnj-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
NMDA receptor antagonist 2；NMDA receptor antagonist 2NMDA receptor antagonist 2 (2024/9/8)
簡介：nmda receptor antagonist 2 is a highly potent and orally active nr2b subtype-selective antagonist of the n-methyl-d-aspartate (nmda) receptor. it exhibits remarkable binding affinities, with an ic50 of 1.0 nm and a ki value of 0.88 nm. this compound finds valuable application in scientific investigations focusing on neuropathic pain and parkinson’s disease.
S-6123；S-6123S-6123 (2024/9/8)
簡介：s-6123 is a highly effective antimicrobial compound classified under the oxazolidinone series, and it acts by selectively inhibiting ribosomal protein synthesis while not affecting dna or rna synthesis.
GLP-1R modulator C16；化合物GLP-1R modulator C16GLP-1R modulator C16；GLP-1R modulator C16 (2024/9/8)
簡介：glp-1r modulator c16 is a variable modulator that significantly increases the binding affinity of glp-4.
Coppersensor 1化合物Coppersensor 1Coppersensor 1|||CS1 (2024/9/8)
簡介：coppersensor 1 (cs1) is a boron dipyrromethene-based fluorescent sensor for selective and sensitive detection of copper(i) ions (cu + ) in biological samples. coppersensor 1 can be imaged using any type of fluorescence microscope, including epifluorescence, confocal and multiphoton.
Violuric acid；紫脲酸Violuric acid (2024/9/8)
簡介：violuric acid is a redox mediator employed in the laccase system, specifically in the context of the violuric acid assay. this assay serves to verify and ensure the preservation of the high-redox potential characteristic of laccase throughout the process of directed evolution.
T-2307；T-2307T-2307 (2024/9/8)
簡介：t-2307, a broad-spectrum arylamidine compound, demonstrates potent antifungal properties both in vitro and in vivo. its activity extends to clinically significant pathogens such as candida species (mic range: 0.00025 to 0.0078 μg/ml), cryptococcus neoformans (mic range: 0.0039 to 0.0625 μg/ml), and aspergillus species (mic range: 0.0156 to 4 μg/ml).
Histone H3 (1-21)；Histone H3 (1-21)Histone H3 (1-21)；Histone H3 (1-21) (2024/9/8)
簡介：histone h3 (1-21) is a truncated form of the histone h3 protein consisting of amino acids 1 to 21. it serves as a common substrate for methyltransferase assays targeting histone 3 at lysine 4 and lysine 9, as well as for acetyltransferase assays targeting histone 3 at lysine 9 and lysine 14.
Acid-PEG8-S-S-PEG8-acid；Acid-PEG8-S-S-PEG8-acidAcid-PEG8-S-S-PEG8-acid；Acid-PEG8-S-S-PEG8-acid (2024/9/8)
簡介：acid-peg8-s-s-peg8-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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