7-Acetoxy-1-methylquinolinium iodide;7-乙酰氧基-1-甲基喹啉溴化物AMQI;7-乙酰氧基-1-甲基喹啉溴化物|||AMQI (2024/9/8)
簡介:7-acetoxy-1-methylquinolinium iodide (amqi) serves as a fluorogenic substrate for cholinesterase, with excitation (ex) occurring at 320 nm and emission (em) at 410 nm. in the fluorometric flow system, the hydrolysis of this compound is employed for the detection and identification of inhibitors.
Methyl-PEG3-bromideMethyl-PEG3-bromideMethyl-PEG3-bromide (2024/9/8)
簡介:methyl-peg3-bromide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
PTP1B-IN-14PTP1B-IN-14PTP1B-IN-14 (2024/9/8)
簡介:ptp1b-in-14 is a selective inhibitor of protein tyrosine phosphatase 1b (ptp1b) that targets the allosteric site, exhibiting an inhibitory concentration (ic50) value of 0.72 μm.
ω-Hydroxy-DEET;ω-Hydroxy-DEETω-Hydroxy-DEET (2024/9/8)
簡介:ω-hydroxy-deet, a significant metabolite of the insect repellent n-n-diethyl-meta-toluamide (deet), exhibits anti-proliferative properties. deet, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.
Ferulic acid acyl-β-D-glucoside;Ferulic acid acyl-β-D-glucosideFerulic acid glucoside|||Ferulic acid (2024/9/8)
簡介:ferulic acid acyl-β-d-glucoside, a metabolite of ferulic acid, is a novel inhibitor of fibroblast growth factor receptor 1 (fgfr1). it exhibits ic50 values of 3.78 μm and 12.5 μm for fgfr1 and fgfr2, respectively.
D-Erythritol 4-phosphate;D-Erythritol 4-phosphateD-Erythritol 4-phosphate (2024/9/8)
簡介:d-erythritol 4-phosphate is a phosphorylated component isolated from the hydrolysate.
2,3,3-Tribromopropenoic acid;2,3,3-Tribromopropenoic acid2,3,3-Tribromopropenoic acid (2024/9/8)
簡介:2,3,3-tribromopropenoic acid is a brominated disinfection byproduct derived from propenoic acid. it is an aromatic compound that possesses polarity. this compound is formed during the chlorination process in water and exhibits cytotoxic properties in chronic cytotoxicity experiments involving mammalian cells.
Bromoiodoacetic acid;溴碘乙酸Bromoiodoacetic acid (2024/9/8)
簡介:bromoiodoacetic acid is a disinfection byproduct (dbp) found in finished drinking waters, belonging to the iodinated haloacids.
5(S)?-?HPETE;5(S)-HPETE5(S)?-?HPETE (2024/9/8)
簡介:5(s)-hydroperoxyeicosatetraenoic acid (5(s)-hpete) is a monohydroperoxy polyunsaturated fatty acid (pufa) generated by the enzymatic conversion of arachidonic acid via 5-lipoxygenase (5-lo). subsequently, 5(s)-hpete undergoes metabolism to form leukotriene a4 (lta4), which serves as a pivotal intermediate in the synthesis of leukotrienes (lts).
AramisulprideAramisulprideR-(+)-Amisulpride|||Aramisulpride (2024/9/8)
簡介:aramisulpride is a dual antagonist of the dopamine d2 receptor and serotonin receptor, primarily utilized for investigating metabolic disorders.
Thiol-C9-PEG4-acid;Thiol-C9-PEG4-acidThiol-C9-PEG4-acid;Thiol-C9-PEG4-acid (2024/9/8)
簡介:thiol-c9-peg4-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
NCGC00029283;化合物NCGC00029283NCGC00029283 (2024/9/8)
簡介:ncgc00029283 is a potent inhibitor of werner syndrome helicase-nuclease (wrn), displaying inhibitory activity against wrn helicase with an ic 50 value of 2.3 μm. additionally, it exhibits inhibitory effects on bloom syndrome protein helicase (blm) and fanconi anemia group j protein helicase (fancj) with ic 50 values of 12.5 μm and 3.4 μm, respectively.
TRPA1 Antagonist 3TRPA1 Antagonist 3TRPA1 Antagonist 3 (2024/9/8)
簡介:trpa1 antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the trpa1 channel, providing the ability for optical control.
Gly6 hydrochloride;Gly6 hydrochlorideHexaglycine hydrochloride;Hexaglycine hydrochloride (2024/9/8)
簡介:gly6 hydrochloride (hexaglycine hydrochloride) is a linear oligopeptide consisting of six glycine units.
Astragaloside;黃芪甲苷Astragaloside (2024/9/8)
簡介:astragaloside, one of the main active ingredients in astragalus membranaceus.
MES sodium saltMES sodium salt2-Morpholinoethanesulphonic acid sodium salt (2024/9/8)
簡介:mes (2-morpholinoethanesulphonic acid) sodium salt, a zwitterionic buffer, is effective in the ph range of 5.5-7.7. mes sodium salt, as one of the good’s buffers, is broadly used to regulate ph value for plants culture medium, reagent solution, and physiological experiments.
Folate-PEG3-amine;Folate-PEG3-amineFolate-PEG3-amine;Folate-PEG3-amine (2024/9/8)
簡介:folate-peg3-amine is a three-unit polyethylene glycol (peg) linker, which is cleavable. this linker is specifically employed in the synthesis of antibody-drug conjugates (adcs).
Luteolin-7-O-β-D-glucopyranoside;Luteolin-7-O-β-D-glucopyranosideLuteolin-7-O-β-D-glucopyranoside (2024/9/8)
簡介:luteolin-7-o-β-d-glucopyranoside is a chemical compound found in the aerial parts of codonopsis nervosa.
Metalaxyl-M;Metalaxyl-MMetalaxyl-M|||(R)-Metalaxyl;Metalaxyl-M|||(R)-Metalaxyl (2024/9/8)
簡介:metalaxyl-m ((r)-metalaxyl), the active (r)-enantiomer of metalaxyl, is a broad-spectrum fungicide that targets protein and ribosomal rna synthesis in fungi. it is employed in the research of plant diseases attributed to pathogens from the oomycota division.
δ-Decalactone;δ-癸內(nèi)酯δ-Decalactone (2024/9/8)
簡介:δ-decalactone is found in nonfat dry milks and fruits and with a sweet taste.
Colominic acid sodium saltColominic acid sodium saltPolysialic acid sodium salt|||Colominic acid sod (2024/9/8)
簡介:colominic acid sodium salt, also known as polysialic acid sodium salt, is naturally isolated from the cell wall of escherichia coli and animals. it exhibits a red color with an absorption maximum of 530 nm and possesses anti-bacterial activity.
Fissistigine A;Fissistigine AFissistigine A (2024/9/8)
簡介:fissistigine a is an alkaloid derived from the basic fractions of formosan fissistigma glaucescens, f. oldhamii, and goniothalamus amuyon.
Benzyl-PEG3-MS;Benzyl-PEG3-MSBenzyl-PEG3-MS;Benzyl-PEG3-MS (2024/9/8)
簡介:benzyl-peg3-ms is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Eflornithine依氟烏氨酸RMI71782|||DFMO|||α-difluoromethylornithine|||MDL71782 (2024/9/8)
簡介:eflornithine (dfmo) is a selective and orally available ornithine decarboxylase inhibitor that delays hair overgrowth.eflornithine is used in the study of african trypanosomiasis, malignant glioma, and sleeping sickness.
Rachelmycin;拉奇霉素NSC298223|||CC-1065;拉奇霉素|||NSC298223|||CC-1065 (2024/9/8)
簡介:rachelmycin (cc-1065; nsc 298223) is a potent naturally antibiotic isolated from streptomyces zelensis . rachelmycin binds non-covalently and covalently (n-3 adenine adduct) in the minor groove of b-form dna. rachelmycin has exceptionally potent antitumor activity.
MPTP hydrochloride;化合物MPTP-hydrochlorideMPTP-hydrochloride;MPTP-hydrochloride (2024/9/8)
簡介:mptp hydrochloride is a precursor of mpp+, a dopamine neurotoxin with blood-brain barrier permeability. mptp hydrochloride is toxic to dopaminergic neurons, which can lead to parkinson´s disease, and is widely used in the construction of animal models of parkinson´s disease.
2α-Methyl androsterone;2α-Methyl androsterone2α-Methyl androsterone (2024/9/8)
簡介:2α-methyl androsterone, a metabolite of mesterolone and drostanolone, is classified as an anabolic androgenic steroid.
Glucocorticoids receptor agonist 1;Glucocorticoids receptor agonist 1Glucocorticoids receptor agonis (2024/9/8)
簡介:glucocorticoids receptor agonist 1 (gra-1) is a highly effective arylpyrazole-based compound that acts as an agonist for the glucocorticoid receptor. gra-1 exhibits strong anti-inflammatory properties while maintaining insulin secretion function.
1,3-Dimethylpyrazole;1,3-二甲基吡唑1,3-Dimethyl-1H-pyrazole|||2,5-Dimethylpyrazole;1,3-Dimethyl-1H-pyrazo (2024/9/8)
簡介:1,3-dimethylpyrazole (2,5-dimethylpyrazole) is a bioactive compound isolated from moso bamboo root.
Dimethylamino-PEG2-C2-NH2;Dimethylamino-PEG2-C2-NH2Dimethylamino-PEG2-C2-NH2;Dimethylamino-PEG2-C2-N (2024/9/8)
簡介:dimethylamino-peg2-c2-nh2 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.