7-TFA-ap-7-Deaza-dG;7-TFA-ap-7-Deaza-dG7-TFA-ap-7-Deaza-dG (2024/9/8)
簡(jiǎn)介:5´-o-tbdms-dg, a modified nucleoside, is utilized in the synthesis of deoxyribonucleic acid or nucleic acid.
PE859;化合物PE859PE859 (2024/9/8)
簡(jiǎn)介:pe859 is a potent inhibitor of both tau and aβ aggregation.
Maltooctaose;MaltooctaoseMaltooctaose (2024/9/8)
簡(jiǎn)介:maltooctaose, a defined maltooligosaccharide with a specific length, can be enzymatically synthesized using pyrococcus furiosus thermostable amylase (pfta).
{Boc}-Phe-Leu-Phe-Leu-Phe;{Boc}-Phe-Leu-Phe-Leu-Phe{Boc}PheLeuPheLeuPhe|||{Boc}-Phe-Leu-Phe-Leu-Phe| (2024/9/8)
簡(jiǎn)介:{boc}-phe-leu-phe-leu-phe ({boc}-flflf) is a selective antagonist of the formyl peptide receptor (fpr) family, effectively inhibiting receptor activity in response to formyl peptides.
Bananin;BananinBananin (2024/9/8)
簡(jiǎn)介:bananin, a potent inhibitor of the atpase activity exhibited by the sars coronavirus helicase, demonstrates remarkable efficacy with an ic50 value of 2.3 μm.
1,2,3,4-Tetrahydro-β-carboline-1-carboxylic acid;1,2,3,4-四氫-β-咔啉-1-羧酸1,2,3,4-Tetrahydro-β-carboline- (2024/9/8)
簡(jiǎn)介:1,2,3,4-tetrahydro-β-carboline-1-carboxylic acid is a neuroactive compound utilized in neurodegenerative disease research.
DMAC-SPDB-sulfo;DMAC-SPDB-sulfoDMAC-SPDB-sulfo (2024/9/8)
簡(jiǎn)介:dmac-spdb-sulfo is a cleavable linker vital in adc synthesis. dmac-spdb-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. the cleavable nature ensures controlled drug release, optimizing adc effectiveness.
DMAC-SPDB;DMAC-SPDBDMAC-SPDB (2024/9/8)
簡(jiǎn)介:dmac-spdb is a cleavable linker vital in adc synthesis. dmac-spdb joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. the cleavable nature ensures controlled drug release, optimizing adc effectiveness.
NO2-SPDMV-sulfo;NO2-SPDMV-sulfoNO2-SPDMV-sulfo;NO2-SPDMV-sulfo (2024/9/8)
簡(jiǎn)介:no2-spdmv-sulfo is a cleavable linker vital in adc synthesis. no2-spdmv-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. the cleavable nature ensures controlled drug release, optimizing adc effectiveness.
NO2-SPDB-sulfo;NO2-SPDB-sulfoNO2-SPDB-sulfo;NO2-SPDB-sulfo (2024/9/8)
簡(jiǎn)介:no2-spdb-sulfo is a cleavable linker vital in adc synthesis. no2-spdb-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. the cleavable nature ensures controlled drug release, optimizing adc effectiveness.
NO2-SPP-sulfo;NO2-SPP-sulfoNO2-SPP-sulfo;NO2-SPP-sulfo (2024/9/8)
簡(jiǎn)介:no2-spp-sulfo is a cleavable linker vital in adc synthesis. no2-spp-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. the cleavable nature ensures controlled drug release, optimizing adc effectiveness.
Mal-PEG2-NH2 TFA;Mal-PEG2-NH2 TFAMal-PEG2-NH2 TFA;Mal-PEG2-NH2 TFA (2024/9/8)
簡(jiǎn)介:mal-peg2-nh2 tfa is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
簡(jiǎn)介:fondaparinux sodium (sr-90107a) is an antithrombin-dependent factor xa inhibitor with antithrombotic activity.
ddCTP;ddCTPddCTP (2024/9/8)
簡(jiǎn)介:ddctp is one of 2´,3´-dideoxyribonucleoside 5´-triphosphates (ddntps) that acts as chain-elongating inhibitor of dna polymerase for dna sequencing.
Hydrastinine;HydrastinineHydrastinine (2024/9/8)
簡(jiǎn)介:hydrastinine, a key alkaloid component found in hydrastis canadensis (goldenseal), serves as an effective hemostatic agent.
1-Stearoyl-2-arachidonoyl-sn-glycerol;1-Stearoyl-2-arachidonoyl-sn-glycerol1-Stearoyl-2-arachidonoyl (2024/9/8)
簡(jiǎn)介:1-stearoyl-2-arachidonoyl-sn-glycerol, a diacylglycerol (dag) encompassing polyunsaturated fatty acids, possesses the ability to activate pkc. moreover, this compound has the potential to enhance nonselective cation channel (nscc) activity.
[Asp5]-Oxytocin;[Asp5]-Oxytocin[Asp5]-Oxytocin;[Asp5]-Oxytocin (2024/9/8)
簡(jiǎn)介:[asp5]-oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity.
Glabrescione B;Glabrescione BGlabrescione B (2024/9/8)
簡(jiǎn)介:glabrescione b is a novel compound that specifically binds to gli1, an important modulator of the hedgehog (hh) signaling pathway. by disrupting the gli1-dna interaction, glabrescione b effectively impairs the activity of gli1. moreover, glabrescione b demonstrates potent inhibitory effects on the growth of tumor cells that rely on hedgehog signaling, as well as on the self-renewal capacity and clonogenicity of tumor-derived stem cells.
m-PEG2-O-Ph-NH2;m-PEG2-O-Ph-NH2m-PEG2-O-Ph-NH2;m-PEG2-O-Ph-NH2 (2024/9/8)
簡(jiǎn)介:m-peg2-o-ph-nh2 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Ibuprofen Impurity F;Ibuprofen Impurity FIbuprofen Impurity F (2024/9/8)
簡(jiǎn)介:ibuprofen impurity f is a known impurity of ibuprofen, which acts as an anti-inflammatory inhibitor that selectively targets both cox-1 and cox-2 enzymes. it exhibits inhibitory activity with ic50 values of 13 μm and 370 μm for cox-1 and cox-2, respectively.
12-Chlorodehydroabietic acid;一氯脫氫松香酸12-Chlorodehydroabietic acid (2024/9/8)
簡(jiǎn)介:12-chlorodehydroabietic acid is a chlorinated resin acid.
12,14-Dichlorodehydroabietic acid;二氯脫氫松香酸12,14-Dichlorodehydroabietic acid (2024/9/8)
簡(jiǎn)介:12,14-dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (bk) channel opening activity. it effectively inhibits gaba-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of gaba a receptors. moreover, 12,14-dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.
Sulfatinib;索凡替尼KDR-IN-1;KDR-IN-1|||索凡替尼 (2024/9/8)
簡(jiǎn)介:sulfatinib (kdr-in-1) (hmpl-012) is a potent and highly selective tyrosine kinase inhibitor against vegfr1/2/3, fgfr1 and csf1r with ic 50 s ranging from 1 to 24 nm.
GSK872 HCl(1346546-69-7 free base);化合物GSK872 HClGSK2399872A;GSK2399872A (2024/9/8)
簡(jiǎn)介:gsk872 hcl(1346546-69-7 free base) (gsk2399872a) is an effective and specific rip3 kinase inhibitor. it binds rip3 kinase domain with high affinity (ic50: 1.8 nm) and inhibits kinase activity (ic50: 1.3 nm).
5α-Cholesta-7,24-dien-3β-ol;5α-Cholesta-7,24-dien-3β-ol5α-Cholesta-7,24-dien-3β-ol (2024/9/8)
簡(jiǎn)介:5α-cholesta-7,24-dien-3β-ol, a sterol, is present in mature spermatozoa of hamster cauda epididymis.
m-PEG7-thiol;m-PEG7-thiolm-PEG7-thiol;m-PEG7-thiol (2024/9/8)
簡(jiǎn)介:m-peg7-thiol is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
PTP1B-IN-13PTP1B-IN-13PTP1B-IN-13 (2024/9/8)
簡(jiǎn)介:ptp1b-in-13, a potent and selective inhibitor of protein tyrosine phosphatase 1b (ptp1b), effectively targets the allosteric site, exhibiting an ic50 value of 1.59 μm.
Eperisone;乙哌立松;艾哌瑞松Eperisone (2024/9/8)
簡(jiǎn)介:eperisone is a centrally acting muscle relaxant and antispastic agent utilized in the treatment of conditions distinguished by muscle stiffness and pain. its mechanism of action involves the relaxation of skeletal muscles and vascular smooth muscles, resulting in a range of beneficial effects including reduction of myotonia, enhancement of circulation, and suppression of the pain reflex. additionally, eperisone exhibits inhibitory properties on the pain reflex pathway and exerts a vasodilator ef
Pigment Red 22;Pigment Red 22Pigment Red 22 (2024/9/8)
簡(jiǎn)介:pigment red 22, a coloring agent, is a versatile compound employed in the formulation of various cosmetic products, including cleansing products, makeup, moisturizers, and night skin care products.
Dracorhodin;血竭素Dracorhodin (2024/9/8)
簡(jiǎn)介:dracorhodin, the primary constituent found in the sanguis draconis extract, is a flavylium compound classified within the anthocyanin family. notably, dracorhodin possesses the ability to elicit vasodilation.