3-Diethylamino-1-propanol;3-二乙氨基-1-丙醇3-Diethylamino-1-propanol (2024/9/8)
簡介:3-diethylamino-1-propanol exhibits anticonvulsant effects.
Neoanhydropodophyllol;NeoanhydropodophyllolNeoanhydropodophyllol (2024/9/8)
簡介:neoanhydropodophyllol, a cyclolignan derivative, exhibits potent antineoplastic activity by exerting cytotoxic effects on various cancer cell lines including leukemia, lung carcinoma, and colon carcinoma.
Methyl-PEG4-acyl chloride;Methyl-PEG4-acyl chlorideMethyl-PEG4-acyl chloride;Methyl-PEG4-acyl chlori (2024/9/8)
簡介:methyl-peg4-acyl chloride is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Heliotrine N-oxide;Heliotrine N-oxideHeliotrine N-oxide (2024/9/8)
簡介:heliotrine n-oxide is the pyrrolizidine alkaloid (pa) n-oxide counterpart of heliotrine. it induces the generation of pyrrolic dna adducts, potentially initiating pa-induced liver tumors in vivo.
m-Tolualdehyde;間甲苯甲醛m-Tolualdehyde (2024/9/8)
簡介:m-tolualdehyde, also known as 3-methylbenzaldehyde, is a chemical compound in the tolualdehyde family featuring a methyl substituent positioned at the 3-position. it finds application as a food additive.
trans-4-Nitrocinnamoyl chloride;trans-4-Nitrocinnamoyl chloridetrans-4-Nitrocinnamoyl chloride (2024/9/8)
簡介:trans-4-nitrocinnamoyl chloride is used as derivatization reagent.
Decaethylene glycol dodecyl ether;Decaethylene glycol dodecyl etherPEG10-dodecyl;PEG10-dodecyl (2024/9/8)
簡介:decaethylene glycol dodecyl ether, a peg-based protac linker, finds utility in protac synthesis.
Ezeprogind;EzeprogindAZP-2006;AZP-2006 (2024/9/8)
簡介:ezeprogind (azp-2006) is an orally active neurotrophic inducer that effectively addresses the underlying factors contributing to neurodegeneration, with a broad scope extending beyond the conventional targets like abeta protein and tau protein. exhibiting potent neuroprotective properties, ezeprogind is a valuable tool for studying a range of neurological disorders, including progressive supranuclear palsy (psp), tauopathies, alzheimer´s disease, parkinson´s disease, and others.
IKK-IN-3;IKK-IN-3IKK-IN-3 (2024/9/8)
簡介:ikk-in-3 is a highly potent and selective inhibitor of ikappab kinase 2 (ikk2 or ikkβ). it exhibits impressive inhibitory activity against ikk2 (ic50 = 19 nm), while also demonstrating significant efficacy against ikk1 (or ikkα) with an ic50 value of 400 nm.
Glycocholic Acid Sodium Salt;甘氨膽酸鈉鹽Glycocholate Sodium|||Sodium Glycocholate;Glycocholate Sodium|||S (2024/9/8)
簡介:glycocholic acid sodium salt (sodium glycocholate) is a conjugated bile salt and ionic biologic detergent. it is involved in the emulsification of fats.
Temocillin disodiumTemocillin disodiumBRL 17421 disodium (2024/9/8)
簡介:temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity.
Methyl 3-hydroxypropanoate;Methyl 3-hydroxypropanoateMethyl 3-hydroxypropanoate (2024/9/8)
簡介:methyl 3-hydroxypropanoate is a protac linker compound, which belongs to the alkyl/ether family. it is commonly employed in the synthesis of protacs.
Glucocorticoids receptor agonist 2;Glucocorticoids receptor agonist 2Glucocorticoids receptor agonis (2024/9/8)
簡介:glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. this compound exhibits potent anti-inflammatory properties without disrupting insulin secretion.
Isouvaretin;IsouvaretinIsouvaretin (2024/9/8)
簡介:isouvaretin demonstrates potent antibacterial activity against b. subtilis and s. epidermidis.
4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid;1-(4-羧基苯基)-3-甲基-5-吡唑酮4-(3-Methyl-5-oxo-2-pyrazolin-1 (2024/9/8)
簡介:4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid exhibits hypoglycemic activity and operates through a mechanism dependent on the response to oral glucose overload.
(E)-2,3-Dibromo-2-butenedioic acid;(E)-2,3-二溴-2-丁二酸(E)-2,3-Dibromo-2-butenedioic acid (2024/9/8)
簡介:(e)-2,3-dibromo-2-butenedioic acid is a brominated haloacid that belongs to the category of drinking water disinfection byproducts (dbps).
Bromodichloroacetonitrile;溴二氯乙腈Bromodichloroacetonitrile (2024/9/8)
簡介:bromodichloroacetonitrile is a nitrogen-containing disinfection byproduct.
Azido-PEG3-chloroacetamide;Azido-PEG3-chloroacetamideAzido-PEG3-chloroacetamide;Azido-PEG3-chloroace (2024/9/8)
簡介:azido-peg3-chloroacetamide is a polyethylene glycol (peg)-based linker. it serves as a crucial component in the synthesis of proteolysis-targeting chimeras (protacs), facilitating efficient conjugation between target protein-recruiting ligands and e3 ubiquitin ligase binders.
(+)-Cinchonaminone;(+)-Cinchonaminone(+)-Cinchonaminone (2024/9/8)
簡介:(+)-cinchonaminone shows monoamine oxidase (mao) inhibitory activity.
Fulvine;FulvineFulvine (2024/9/8)
簡介:fulvine, a pyrrolizidine alkaloid extracted from crotalaria fulva seeds, exhibits hepatotoxic properties and can be employed for inducing hypertensive pulmonary vascular disease in vivo.
1,1,1,3,10,11-Hexachloroundecane;1,1,1,3,10,11-Hexachloroundecane1,1,1,3,10,11-Hexachloroundecane (2024/9/8)
簡介:1,1,1,3,10,11-hexachloroundecane is a polychlorinated alkane (pca) characterized by a lengthy carbon chain.
Tiazofurin;噻唑呋林NSC 286193|||Riboxamide;NSC 286193|||Riboxamide|||噻唑呋林 (2024/9/8)
簡介:tiazofurin (nsc-286193) is a synthetic nucleoside analogue with antineoplastic activity. tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (tad), a potent imp dehydrogenase (impdh) inhibitor.
26RFa Acetate (mouse,rat);26RFa 醋酸(大鼠,小鼠)Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (6001 (2024/9/8)
簡介:orphan gpcr sp9155 agonist p550 (mouse, rat) acetate (orphan gpcr sp9155 agonist p550 ) is a member of the rfamide peptide family with orexigenic effects.
Orphan GPCR SP9155 agonist P550 (mouse, rat);Orphan GPCR SP9155 agonist P550 (mouse, rat)26RFa (mous (2024/9/8)
簡介:orphan gpcr sp9155 agonist p550 (mouse, rat) (26rfa (mouse, rat)) is an orphan gpcr with an orexigenic effect belonging to the rfamide peptide family. it acts as the cognate ligand for the mouse orphan receptor gpr103, which is also known as sp9155 or aq27.
N-Nitrosomorpholine;N-亞硝基嗎啉N-Nitrosomorpholine (2024/9/8)
簡介:n-nitrosomorpholine, a nitrosamine compound, exhibits sensitivity to light and is recognized as a potent carcinogen in animals.
Diiodoacetic acid;二碘乙酸Diiodoacetic acid (2024/9/8)
簡介:diiodoacetic acid is a disinfection by-product (dbp) formed during water disinfection.
2,2-Dibromoacetamide;2,2-Dibromoacetamide2,2-Dibromoacetamide (2024/9/8)
簡介:2,2-dibromoacetamide is a class of disinfection by-product (dbp) in drinking water.
[Tyr11]-Somatostatin;[Tyr11]-Somatostatin[Tyr11]-Somatostatin;[Tyr11]-Somatostatin (2024/9/8)
簡介:[tyr11]-somatostatin is a neuroactive peptide utilized in proteomics research. it belongs to a class of neuroactive substances that play a role in modulating retinal physiology.
E6446 dihydrochloride;化合物E6446 dihydrochlorideE6446 dihydrochloride (2024/9/8)
簡介:e6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing tlrs; potently suppressed dna stimulation of hek:tlr9 cells with ic50 of 10 nm.
[Tyr1]-Somatostatin-14;[Tyr1]-Somatostatin-14[Tyr1]-Somatostatin-14;[Tyr1]-Somatostatin-14 (2024/9/8)
簡介:[tyr1]-somatostatin-14 could binds to sstr2.