9月
Isoanthricin；Isoanthricin(Rac)-Deoxypodophyllotoxin；(Rac)-Deoxypodophyllotoxin (2024/9/8)
簡(jiǎn)介：isoanthricin, also known as (rac)-deoxypodophyllotoxin, is the racemate form of deoxypodophyllotoxin, a powerful compound with noteworthy antitumor and anti-inflammatory properties.
Poloxamer 188；泊洛沙姆 188Poloxamer 188 (2024/9/8)
簡(jiǎn)介：poloxamer 188, a nonionic linear copolymer possessing surfactant properties, demonstrates anti-thrombotic, anti-inflammatory, and cytoprotective activities across different tissue injury models.
Leonurine hydrochloride；鹽酸益母草堿SCM-198 hydrochloride|||SCM-198 HCl；鹽酸益母草堿|||SCM-198 hydrochloride|||S (2024/9/8)
簡(jiǎn)介：leonurine hydrochloride (scm-198 hydrochloride) , a major alkaloid compound extracted from leonurus japonicas houtt. (labiatae), is considered to have antitumor roles.
ddGTP；ddGTP2′,3′-Dideoxyguanosine 5′-triphosphate|||ddGTP；2′,3′-Dideoxyguanosine 5′-triphosphate|||d (2024/9/8)
簡(jiǎn)介：ddgtp (2′,3′-dideoxyguanosine 5′-triphosphate) is one of 2´,3´-dideoxyribonucleoside 5´-triphosphates (ddntps) that acts as chain-elongating inhibitor of dna polymerase for dna sequencing.
Triflumizole；TriflumizoleTriflumizole (2024/9/8)
簡(jiǎn)介：triflumizole, an imidazole fungicide, acts as an inhibitor of ergosterol biosynthesis. this widely utilized compound effectively controls powdery mildew and scabs on a range of fruits and crops.
Essential oils, Melaleuca alternifolia；Essential oils, Melaleuca alternifoliaEssential oils, Melaleu (2024/9/8)
簡(jiǎn)介：melaleuca alternifolia essential oil, derived from the leaves of melaleuca alternifolia, exhibits bactericidal and anti-inflammatory properties.
5β-Dihydrocortisone；5β-Dihydrocortisone5β-Dihydrocortisone (2024/9/8)
簡(jiǎn)介：5β-dihydrocortisone, a sterol metabolite derived from cortisone, is produced in the liver through the action of 5β-reductase (akr1d1).
BNTA；化合物BNTABNTA (2024/9/8)
簡(jiǎn)介：bnta is a potent extracellular matrix (ecm) modulator. in a rat model of arthritis, bnta modulates arthritis by promoting the synthesis of cartilage structural molecules on chondrocytes through the induction of superoxide dismutase 3 (sod3) and regulating chondrogenesis through superoxide anion elimination.
HEPPSO；HEPPSOHEPPSO (2024/9/8)
簡(jiǎn)介：heppso is a zwitterionic buffer with a working ph range of 7.1-8.5. it exhibits strong copper(ii) binding capability and a pk value of 7.84 at a concentration of 2.0 mm.
2-Bromoacetamide；2-溴乙酰胺2-Bromoacetamide (2024/9/8)
簡(jiǎn)介：2-bromoacetamide can inactivate alcohol dehydrogenase.
Cu(II)GTSM；Cu(II)GTSMCu(II)GTSM (2024/9/8)
簡(jiǎn)介：cu(ii)gtsm, a cell-permeable copper-complex, effectively inhibits gsk3β and shows inhibitory effects against amyloid-β oligomers (aβos) while reducing tau phosphorylation. additionally, cu(ii)gtsm decreases the abundance of amyloid-β trimers. with its potential as an anticancer and antimicrobial agent, cu(ii)gtsm exhibits promising therapeutic capabilities.
CuATSP；CuATSPCuATSP (2024/9/8)
簡(jiǎn)介：cuatsp, a significantly potent inhibitor of ferroptotic cell death, exhibits nearly 20 times the efficacy of cuatsm.
ω-Muricholic Acid；ω-Muricholic Acidω-Muricholic Acid (2024/9/8)
簡(jiǎn)介：ω-muricholic acid (ω-mca) is a murine-specific secondary bile acid.
簡(jiǎn)介：ly-294002 hydrochloride (nsc 697286) is a synthetic molecule inhibitor of pi3kα/δ/β (ic50: 0.5/0.57/0.97 μm, in cell-free assays); more stable than wortmannin in solution, and also is a blocker of autophagosome formation.
Eflornithine hydrochloride；鹽酸依氟烏氨酸MDL71782hydrochloride|||RMI71782hydrochloride|||DFMO hydrochloride (2024/9/8)
簡(jiǎn)介：eflornithine hydrochloride, a specific and irreversible inhibitor of ornithine decarboxylase enzyme, is a medication used for the treatment of african trypanosomiasis and excessive facial hair growth in women.
PYBG；PYBGPYBG (2024/9/8)
簡(jiǎn)介：pybg serves as a flexible precursor for facile conjugation with diverse fluorescent dyes using ´click chemistry´ and sonogashira coupling reactions.
Platyconic acid A；Platyconic acid APlatyconic acid A (2024/9/8)
簡(jiǎn)介：platyconic acid a, derived from changkil saponins extracted from platycodon grandiflorum, is a potent compound employed for studying the mitigation of airway inflammation.
Gefitinib impurity 1；Gefitinib impurity 1Gefitinib impurity 1 (2024/9/8)
簡(jiǎn)介：gefitinib impurity 1 is a compound derived from gefitinib, a potent and selective egfr tyrosine kinase inhibitor (ic 50 = 33 nm). this orally active compound selectively inhibits tumor cell growth stimulated by egf (ic 50 = 54 nm) and inhibits egfr autophosphorylation induced by egf in tumor cells. additionally, gefitinib induces autophagy and exhibits antitumor activity.
Kansuinine E；Kansuinine EKansuinine E (2024/9/8)
簡(jiǎn)介：kansuinine e, a jatrophane-type diterpenoid, is a plant-derived compound isolated from the roots of e. kansui. it functions as a nitric oxide inhibitor, with an inhibitory concentration of 6.3 μm (ic50).
Metazachlor；甲氧氯胺Metazachlor (2024/9/8)
簡(jiǎn)介：metazachlor, a member of the chloroacetamide class of herbicides, acts as a long chain fatty acid synthesis inhibitor. it exerts an influence on cell division and tissue differentiation in germinating and emerging weed species.
Geranylgeranyl pyrophosphate, t-BA (1:2)；Geranylgeranyl pyrophosphate 叔丁胺 (1:2)Geranylgeranyl pyroph (2024/9/8)
簡(jiǎn)介：geranylgeranyl pyrophosphate tetrabutylammonium(1：2) is one of the endogenous cholesterol and intermediates produced by the mevalerate pathway. geranylgeranyl pyrophosphate tetrabutylammonium(1：2) is the common precursor of diterpenoids, for example, paclitaxel. it can be used for cancer research.
Geranylgeranyl pyrophosphate, t-BA (1:1.5)；Geranylgeranyl pyrophosphate 叔丁胺 (1:1.5)Geranylgeranyl py (2024/9/8)
簡(jiǎn)介：(2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl dihydrogen diphosphate,tetrabutylammonium(1:1.5) is a common precursor of taxadiene such as paclitaxel.
Geranylgeranyl pyrophosphate；Geranylgeranyl pyrophosphateGeranylgeranyl pyrophosphate (2024/9/8)
簡(jiǎn)介：geranylgeranyl pyrophosphate, a key metabolite in protein geranylgeranylation, serves as the universal precursor for diterpenoids, such as paclitaxel. its role in cancer research stems from this critical function.
THP-PEG9-OH；THP-PEG9-OHTHP-PEG9-OH；THP-PEG9-OH (2024/9/8)
簡(jiǎn)介：thp-peg9-oh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
SB 242235化合物SB242235SB-242235|||SB242235 (2024/9/8)
簡(jiǎn)介：sb 242235 is a potent and selective p38 map kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.
Benzyl-PEG9-THP；Benzyl-PEG9-THPBenzyl-PEG9-THP；Benzyl-PEG9-THP (2024/9/8)
簡(jiǎn)介：benzyl-peg9-thp is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tyrosylleucine TFA；Tyrosylleucine TFATyr-Leu TFA；Tyr-Leu TFA (2024/9/8)
簡(jiǎn)介：tyrosylleucine (tyr-leu, yl) tfa is a dipeptide compound with potent antidepressant-like activity. this orally active compound demonstrates effective modulation of depressive symptoms.
EncainideEncainideEncainide|||MJ9067 (2024/9/8)
簡(jiǎn)介：encainide (mj9067), a class ic antiarrhythmic drug, holds potential for research into life-threatening and symptomatic ventricular arrhythmias as well as supraventricular arrhythmias.
Diguanosine 5′-triphosphate；Diguanosine 5′-triphosphateDiguanosine 5′-triphosphate|||Gp3G；Diguanosin (2024/9/8)
簡(jiǎn)介：diguanosine 5′-triphosphate (gp3g) is a kind of homodinucleotide from by gtp:gtp guanylyltransferase. diguanosine 5′-triphosphate is a virus-specific oligonucleotide, can be used to prime reovirus transcription and inhibit rna methylation.
SSR411298；SSR411298SSR411298；SSR411298 (2024/9/8)
簡(jiǎn)介：ssr411298 is a reversible, orally active compound that selectively inhibits fatty acid amide hydrolase (faah). its potential lies in the field of post-traumatic stress disorder (ptsd) research.
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