9月
2,2-Dibromopropanoic acid；2,2-Dibromopropanoic acid2,2-Dibromopropanoic acid (2024/9/8)
簡介：2,2-dibromopropanoic acid is a derivative of propionic acid, characterized by the presence of two bromine atoms. propionic acid, which belongs to the category of short chain fatty acids, serves as a chemical intermediate. additionally, propionic acid acts as a mold inhibitor and finds extensive usage as a food preservative.
Erythromycin A dihydrate；Erythromycin A dihydrateErythromycin A dihydrate (2024/9/8)
簡介：erythromycin dihyrate dihydrate is a macrolide antibiotic produced by actinomycete streptomyces erythreus with a broad spectrum of antimicrobial activity. erythromycin dihyrate acts by binding to bacterial 50s ribosomal subunits and inhibits rna-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid.
CP-610431；CP-610431CP-610431 (2024/9/8)
簡介：cp-610431 is a reversible, atp-uncompetitive inhibitor of acetyl-coa carboxylase (acc), exhibiting isozyme nonselectivity. it inhibits both acc1 and acc2 with ic50 values of approximately 50 nm. cp-610431 offers potential application in metabolic syndrome research.
Ioxaglic acid；碘克沙酸P-286；碘克沙酸|||P-286 (2024/9/8)
簡介：ioxaglic acid (p-286) is a negatively charged contrast agent commonly utilized as an inverse indicator for glycosaminoglycan (gag) in computed tomography (ct). this compound is valuable for imaging human osteoarthritic cartilage, enabling the quantitative assessment of glycosaminoglycan content.
Benzyl-PEG1-Ms；Benzyl-PEG1-MsBenzyl-PEG1-Ms；Benzyl-PEG1-Ms (2024/9/8)
簡介：benzyl-peg1-ms is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bacoside A2假馬齒莧素A2假馬齒莧素A2 (2024/9/8)
簡介：bacoside a2 is a triterpenoid saponin.
7-Deaza-7-propargylamino-dGTP；7-Deaza-7-propargylamino-dGTP7-Deaza-7-propargylamino-dGTP (2024/9/8)
簡介：7-deaza-7-propargylamino-dgtp is an analogue of dgtp, specifically designed for the purpose of gene sequencing.
7-Deaza-7-propargylamino-dATP；7-Deaza-7-propargylamino-dATP7-Deaza-7-propargylamino-dATP (2024/9/8)
簡介：7-deaza-7-propargylamino-datp is a deoxyadenosine triphosphate (datp) analog utilized in the field of gene sequencing.
VLX1570；化合物VLX1570VLX1570 (2024/9/8)
簡介：vlx1570 is a competitive inhibitor of proteasome dub activity with ic50 ranging from 4.2 um to 8.6 um. it has potent inhibition for usp14.
Diiodoacetamide；DiiodoacetamideDiiodoacetamide (2024/9/8)
簡介：diiodoacetamide, an iodo-haloacetamide compound, emerges as a disinfection by-product (dbp) within drinking water.
N-Palmitoyl-L-glutamine；N-Palmitoyl-L-glutamineN-Palmitoyl-L-glutamine (2024/9/8)
簡介：n-palmitoyl-l-glutamine is a glutamine derivative.
L-Azatyrosine；L-AzatyrosineL-Azatyrosine (2024/9/8)
簡介：l-azatyrosine, an antitumor antibiotic derived from streptomyces chibaensis, exhibits the ability to restore the normal phenotypic behavior of transformed cells that carry oncogenic ras genes.
Cyclo(Gly-Tyr)；Cyclo(Gly-Tyr)Cyclo(Gly-Tyr) (2024/9/8)
簡介：cyclo(gly-tyr) is a cyclic dipeptide.
Uvaretin；UvaretinUvaretin (2024/9/8)
簡介：uvaretin demonstrates potent antibacterial activity against b. subtilis (ec50: 8.7 μm) and s. epidermidis (ic50: 7.9 μm).
Methyl acetate-PEG1；Methyl acetate-PEG1Methyl acetate-PEG1；Methyl acetate-PEG1 (2024/9/8)
簡介：methyl acetate-peg1 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
9,10-Dichlorostearic acid；9,10-二氯骨酸；9,10-二氯硬脂酸9,10-Dichlorostearic acid (2024/9/8)
簡介：9,10-dichlorostearic acid is a chlorinated stearic acid that possesses antimutagenic properties. in vitro studies show that this compound induces membrane damage in mammalian tumor cells by causing leakage of adenosine triphosphate (atp).
Isepamicin；IsepamicinSch 21420；Sch 21420 (2024/9/8)
簡介：isepamicin (sch 21420) is a potent aminoglycoside antibacterial compound with enhanced efficacy against strains harboring type i 6´-acetyltransferase. its antibacterial spectrum encompasses enterobacteriaceae and staphylococci, while exhibiting resistance against anaerobes, neisseriaceae, and streptococci. moreover, isepamicin displays a robust concentration-dependent bactericidal effect, a prolonged post-antibiotic effect lasting several hours, and is capable of inducing adaptive resistan
ML-60218；化合物ML-60218ML-60218 (2024/9/8)
簡介：ml-60218 is an inhibitor of broad-spectrum rna pol iii with ic50s of 32 and 27 μm for saccharomyces cerevisiae and human. ml-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms.
Kansuinine B；甘遂萜酯BKansuinine B (2024/9/8)
簡介：kansuinine b inhibits stat3 activation induced by il-6. kansuinine b exhibits anti-viral activity and could be used in covid-19 research.
FIN56；化合物FIN56FIN56 (2024/9/8)
簡介：fin56 is a specific inducer of ferroptosis.
γ-Acetylenic GABA hydrochloride；化合物γ-Acetylenic GABA鹽酸鹽γ-Acetylenic GABA hydrochloride(57659-38-8 Fr (2024/9/8)
簡介：γ-acetylenic gaba hydrochloride is a gaba transaminase inhibitor.
γ-Acetylenic GABAγ-Acetylenic GABA4-Aminohex-5-ynoic acid|||γ-Acetylenic GABA (2024/9/8)
簡介：γ-acetylenic gaba (4-aminohex-5-ynoic acid) is a potent, irreversible inhibitor of gaba-transaminase. this compound effectively raises the concentration of γ-aminobutyric acid (gaba) in the brain of rats.
[D-Asn5]-Oxytocin；[D-Asn5]-Oxytocin[D-Asn5]-Oxytocin；[D-Asn5]-Oxytocin (2024/9/8)
簡介：[d-asn5]-oxytocin exhibits minimal specific oxytocic and vasodepressor effects. comparative cumulative dose-response investigations reveal that [d-asn5]-oxytocin demonstrates a similar intrinsic activity to oxytocin in terms of oxytocic activity.
Epiquinidine；表奎寧定Epiquinidine (2024/9/8)
簡介：epiquinidine, an analogue of quinine, serves as an agonist for ggtas2r1, exhibiting activation at concentrations of 10 μm or higher.
Chlorobenzuron；滅幼脲Chlorobenzuron (2024/9/8)
簡介：chlorobenzuron is a chitin synthetase inhibitor, acts as an insecticide. chlorobenzuron inhibits larvae development and pupate.
3,4,5-Trichloroguaiacol；3,4,5-三氯愈創(chuàng)木酚3,4,5-Trichloroguaiacol (2024/9/8)
簡介：3,4,5-trichloroguaiacol is a phenolic compound that is commonly found in the effluents originating from bleached kraft pulp mills.
Avatrombopag hydrochloride；Avatrombopag hydrochlorideAKR-501 hydrochloride|||YM477hydrochloride|||E5 (2024/9/8)
簡介：avatrombopag hydrochloride (akr-501) is an orally active, nonpeptide agonist of the thrombopoietin (tpo) receptor with an ec 50 of 3.3 nm. it effectively mimics the biological activities of tpo, stimulating platelet production by activating the intracellular signaling system and facilitating the generation of platelets and megakaryocytes from hemopoietic precursor cells. additionally, avatrombopag hydrochloride serves as a substrate for cytochrome p450 (cyp) 2c9 and cyp3a.
Meclizine；美克洛嗪Meclozine；Meclozine (2024/9/8)
簡介：meclizine, also known as meclozine, is a piperazine class h1 antagonist with antihistamine properties that inhibits the interaction of histamine at h1 receptors reversibly. it serves as an effective anti-motion sickness agent, able to cross the blood-brain barrier. additionally, meclizine acts as an agonist ligand for the mouse constitutive androstane receptor (car) and an inverse agonist for human car, making it useful in research on polyq toxicity disorders, including huntington´s diseas
3,4,5-Trichlorocatechol；3,4,5-三氯兒茶；3,4,5-三氯鄰苯二酚3,4,5-Trichlorocatechol (2024/9/8)
簡介：3,4,5-trichlorocatechol is a derivative of catechol that is derived from pentachlorophenol. it is known to induce oxidative lesions in dna.
Dihydroisopimaric acid；二氫異海松酸Dihydroisopimaric acid (2024/9/8)
簡介：dihydroisopimaric acid activates bk channels alphabeta1, which are large conductance ca 2+ activated k + channels. this compound directly measures the opening of bkalphabeta1 under a whole-cell voltage clamp.
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