9月
Pomalidomide-C6-I TFA；化合物Pomalidomide-C6-I TFAPomalidomide-C6-I TFA (2024/9/8)
簡介：pomalidomide-c6-i tfa is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Pomalidomide-C5-COOH；化合物Pomalidomide-C5-COOHPomalidomide-C5-COOH (2024/9/8)
簡介：pomalidomide-c5-cooh is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Pomalidomide-CH2CONH-C2-COOH；化合物Pomalidomide-CH2CONH-C2-COOHPomalidomide-CH2CONH-C2-COOH (2024/9/8)
簡介：pomalidomide-ch2conh-c2-cooh is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Pomalidomide-C2-COOH；化合物Pomalidomide-C2-COOHPomalidomide-C2-COOH (2024/9/8)
簡介：pomalidomide-c2-cooh is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Pomalidomide-C7-NH2 hydrochloride；化合物Pomalidomide-C7-NH2 hydrochloridePomalidomide-C7-NH2 hydrochlor (2024/9/8)
簡介：pomalidomide-c7-nh2 hydrochloride is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Thalidomide-NH-C6-NH2 hydrochloride；化合物Pomalidomide-C6-NH2 hydrochlorideThalidomide-NH-C6-NH2 hydroc (2024/9/8)
簡介：pomalidomide-c6-nh2 hydrochloride is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Pomalidomide-C3-NH2 hydrochloride；化合物Pomalidomide-C3-NH2 hydrochloridePomalidomide-C3-NH2 hydrochlor (2024/9/8)
簡介：pomalidomide-c3-nh2 hydrochloride is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Pomalidomide-C6-COOH；化合物Pomalidomide-C6-COOHPomalidomide-C6-COOH (2024/9/8)
簡介：pomalidomide-c6-cooh is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
Pomalidomide-C3-I；化合物Pomalidomide-C3-IPomalidomide-C3-I (2024/9/8)
簡介：pomalidomide-c3-i is a synthesized e3 ligase ligand-linker conjugate that incorporates the pomalidomide based crbn ligand and linker used in protac technology.
(±)-Equol；(±)-雌馬酚Equol|||(R,S)-Equol；Equol|||(±)-雌馬酚|||(R,S)-Equol (2024/9/8)
簡介：(±)-equol ((r,s)-equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. the estrogen receptor (er) agonist activity of the naturally occurring (s)-enantiomer (ec50 = 85 and 65 nm for human erα and erβ, respectively) is similar to that of genistein but exceeds that of daidzein. (±)-equol preferentially binds erβ (ki = 0.73 nm) and demonstrates approximately 9-fold lower affinity for erα (ki = 6.41 nm). (±)-equol is
Caftaric acid；單咖啡酰灑石酸t(yī)rans-Caftaric acid；trans-Caftaric acid|||單咖啡酰灑石酸 (2024/9/8)
簡介：caftaric acid (trans-caftaric acid) is a natural product with antioxidant and anti-inflammatory properties, antimutagenicity, and an inhibitor of protein-protein interactions mediated by src family kinases.
Perillene；紫蘇烯3-Isohexenylfuran|||Perillen；3-Isohexenylfuran|||紫蘇烯|||Perillen (2024/9/8)
簡介：perillene (3-isohexenylfuran) is an actiive constituent in the drug which promotes enterocinesia. perillen demonstrates strong resistance activity against staphylococcus aureus and e.coli.
7-epi-Taxol；7-表紫杉醇7-Epitaxol|||7-epi-Paclitaxel；7-Epitaxol|||7-表紫杉醇|||7-epi-Paclitaxel (2024/9/8)
簡介：1. 7-epi-taxol (7-epitaxol) is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.
β,β-Dimethylacrylshikonin；β,β-二甲基丙烯酰紫草素Dimethylacrylshikonin|||β, β-Dimethylacrylshikonin；β,β-二甲基丙烯酰 (2024/9/8)
簡介：1. β,β-dimethylacrylshikonin (dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) injection of dimethylacrylshikonin combined with ir treatment significantly suppressed tumor growth of the hct-116 xenograft. (b) dimethylacrylshikonin significantly suppressed the growth of h(22) transplantable hepatoma, and induced the activation of caspase-3 . (c) dimethylacrylshikonin inhibited growth of gastric cancer sgc-791 cells by inducing er
Usaramine；光萼野百合堿(15E)-Retrorsine|||Mucronatine|||NISTC15503874；(15E)-Retrorsine|||Mucronatine|||光萼野百 (2024/9/8)
簡介：usaramine (mucronatine) demonstrates phytotoxicity against lactuca sativa var. carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.
Ardisiacrispin A；百兩金素Saxifragifolin B|||LTS-4|||Deglucocyclamin；百兩金素|||Saxifragifolin B|||LTS-4|||De (2024/9/8)
簡介：ardisiacrispin a (deglucocyclamin) has cytotoxic activity toward hepg2 cancer cell with the gi(50) value of 1.56μm, it could inhibit the proliferation of bel-7402 cells by inducing apoptosis and disassembling microtubule.ardisiacrispin(a+b) exhibit prominent abilities to inhibit the proliferation of hl-60 cells by blocking the cell cycle at s phase and inducing apoptosis.
Poncirin；枸橘苷Isosakuranetin-7-neohesperidoside；枸橘苷|||Isosakuranetin-7-neohesperidoside (2024/9/8)
簡介：1. poncirin (isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, sgc-791, in a dose-dependent manner. 2. poncirin prevents adipogenesis, enhances osteoblast differentiation in mesenchymal stem cellsincreased bone mineral density, and improves trabecular microarchitecture likely reflect increases bone formation and decreases bone resorption in gio mice.
Gardenoside羥異梔子苷羥異梔子苷|||梔子苷 (2024/9/8)
簡介：gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against nash by suppressed supernatant inflammatory cytokine production and intracellular nfkb activity. gardenoside may be considered potential drug candidates that target p2x3 and p2x7 purine receptors.
Methyl eugenol；甲基丁香酚4-allylveratrole|||eugenyl methyl ether|||O-methyleugenol|||Eugenol Methyl ether (2024/9/8)
簡介：1. methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of me, the need to check its presence in food products with effective analytical methods. 2. methyleugenol has insecticidal properties. 3. methyleugenol can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro
Lancerin；4-β-D-葡萄糖基-1,3,7-三羥基呫噸酮Lancerin (2024/9/8)
簡介：lancerin, extracted from the root bark of cudrania cochinchinensis, exhibits antioxidative activity against lipid peroxidation.
Polygalic acid；遠(yuǎn)志皂甙Senegenic acid；Senegenic acid|||遠(yuǎn)志皂甙 (2024/9/8)
簡介：polygalic acid (senegenic acid), a triterpenoid saponin, is a major active ingredient in polygala tenuifolia. polygalic acid shows expectorant, emetic and stimulant effects.
Chrysin 7-O-beta-gentiobioside；白楊素-7-O-龍膽二糖Chrysin 7-O-β-gentiobioside；Chrysin 7-O-β-gentiobioside|| (2024/9/8)
簡介：chrysin 7-o-beta-gentiobioside (chrysin 7-o-β-gentiobioside), a glycosylation product of chrysin, is from spartium junceum.
23-Hydroxybetulinic acid；23-羥基白樺酸Anemosapogenin；Anemosapogenin|||23-羥基白樺酸 (2024/9/8)
簡介：23-hydroxybetulinic acid (anemosapogenin) shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed.
N-Benzylpalmitamide；N-芐基十六烷酰胺Macamide 1|||N-Benzylhexadecanamide；Macamide 1|||瑪卡酰胺 B|||N-芐基十六烷酰胺|||N (2024/9/8)
簡介：n-benzylpalmitamide (macamide 1) inhibits fatty acid amide hydrolase (faah) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and cns degenerative disorders.
(-)-Securinine；一葉秋堿Securinine；一葉秋堿|||Securinine (2024/9/8)
簡介：(-)-securinine (securinine) is plant-derived alkaloid and also a gabaa receptor antagonist.
3-Butylidenephthalide；丁烯基苯酞Butylidene phthalide|||n-Butylidenephthalide；Butylidene phthalide|||n-But (2024/9/8)
簡介：1. 3-butylidenephthalide (butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (ic(5) 2.35 mm) in a noncompetitive fashion with a k(i) of 4.86 mm.
Rubusoside；甜茶苷Rubusoside (2024/9/8)
簡介：1. rubusoside is a natural sweetener . 2. rubusoside is a solubilizing agent with antiangiogenic and antiallergic properties.
Lathyrol；千金子二萜醇Lathyrol (2024/9/8)
簡介：1.lathyrol diterpenes is a modulator of p-glycoprotein dependent multidrug resistance.
Epoxylathyrol；環(huán)氧續(xù)隨子醇Epoxylathyrol (2024/9/8)
簡介：epoxylathyrol derivatives have modulation of abcb1-mediated multidrug resistance in human colon adenocarcinoma and mouse t-lymphoma cells.
MRE-269；3-氧代-12-烯-28-烏蘇酸3-氧代-12-烯-28-烏蘇酸|||ACT-333679|||ACT-333679|||MRE-269|||MRE-269|||MRE 269|||M (2024/9/8)
簡介：mre-269 (act-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. mre-269(act-333679) is used for the treatment of pulmonary arterial hypertension. mre-269(act-333679) is an active metabolite of selexipag (s253150).
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