9月
ML241 hydrochloride；化合物ML241 hydrochlorideML241 hydrochloride (2024/9/8)
簡介：ml241 is a potent and selective inhibitors of p97 atpase.ml241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-reporter cell line. ml241 may be a novel agent for the chemotherapy of cancer, and provide a rationale for developing pathway-specific p97 inhibitors.
T863；化合物T863DGAT-3|||DGAT-1 inhibitor；DGAT-3|||DGAT-1 inhibitor (2024/9/8)
簡介：t-863(dgat-1 inhibitor) is an orally active, selective and potent dgat1 (acyl-coa:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-coa binding site of dgat1, and inhibits triacylglycerol synthesis in cells. ic50 value: target: dgat1 t863 (dgat-3) causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.
HC-067047；化合物HC-067047HC067047；HC067047 (2024/9/8)
簡介：hc-067047 is a potent and selective trpv4 antagonist.also inhibits the endogenous trpv4-mediated response to 4α-pdh .
WM-1119化合物WM-1119WM1119 (2024/9/8)
簡介：wm-1119 is a highly potent, selective kat6a/b inhibitor
Fmoc-Val-Cit-PAB；化合物Fmoc-Val-Cit-PABFmoc-Val-Cit-PAB (2024/9/8)
簡介：fmoc-val-cit-pab is a linker for antibody-drug-conjugation (adc).
MMAD；單甲基澳瑞他汀 DMonomethylauristatin D|||Demethyldolastatin 10|||Monomethyl Dolastatin 10；Monomethylau (2024/9/8)
簡介：mmad (demethyldolastatin 10) is a potent tubulin inhibitor. mmad is a toxin payload in antibody drug conjugates (adcs).
Sardomozide dihydrochloride；Sardomozide 鹽酸鹽CGP 48664 dihydrochloride|||Sardomozide dihydrochloride；C (2024/9/8)
簡介：sardomozide dihydrochloride (cgp 48664 dihydrochloride) is an inhibitor of s-adenosylmethionine decarboxylase (samdc, ic50 = 5 nm).
4-Carboxyisothiazole；4-羧基異噻唑4-Carboxyisothiazole (2024/9/8)
簡介：4-carboxyisothiazole 用作中間體。
SB297006；化合物SB 297006SB 297006；SB 297006 (2024/9/8)
簡介：sb297006 is an antagonist of c-c chemokine receptor 3 (ccr3; ic50 = 39 nm), which normally is activated by eotaxin, eotaxin-3, mcp-3, mcp-4, rantes, and mip-1δ. it is at least 250-fold selective for ccr3 over a panel of other chemokine receptors. sb 297006 blocks ccr3-mediated calcium mobilization induced by eotaxin, eotaxin-2, and mcp-4 in transfected cells. it suppresses antigen-induced accumulation of th2 lymphocytes and eosinophils in lungs of mice when delivered subcutaneously (100 mg/kg).
Brevilin A；短葉老鸛草素ABrevilin A (2024/9/8)
簡介：brevilin a is a sesquiterpene lactone isolated from centipeda minima, inhibits janus kinase activity and blocks stat3 signaling in cancer cells with anti-tumor activity. brevilin a is a selective inhibitor of jak-stat signal pathway by attenuating the jaks activity and blocking stat3 signaling (ic50 = 10.6 μm) in cancer cells.brevilin a induces apoptosis and autophagy via mitochondrial pathway and pi3k/akt/mtor inactivation in colon adenocarcinoma cell ct26.antitumour
BN82002；化合物CDC25 Phosphatase Inhibitor ICDC25 Phosphatase Inhibitor I；CDC25 Phosphatase Inhibitor I (2024/9/8)
簡介：bn82002 (cdc25 phosphatase inhibitor i) is a synthetic inhibitor of cdc25 phophatases
SR0987；化合物SR0987SR0987 (2024/9/8)
簡介：sr0987 is a rorγt agonist,
Fantofarone；泛托法隆SR 33557；SR 33557|||泛托法隆 (2024/9/8)
簡介：fantofarone (sr 33557) is a highly potent antagonist of calcium channel.
ABT-702 dihydrochloride；化合物ABT-702 dihydrochlorideABT-702 dihydrochloride (2024/9/8)
簡介：abt-702 dihydrochloride is a potent adenosine kinase (ak) inhibitor.
EOS-62062化合物 T4667EOS 62062|||EOS62062|||EOS-62062 (2024/9/8)
簡介：pesampator (pf-04958242) is a potent, highly selective positive allosteric modulator of the ampa receptor, also known as an ampa potentiator, demonstrating an ec50 of 310 nm and a ki of 170 nm [1].
TCJL37；化合物 T4666TCJL37 (2024/9/8)
簡介：tcjl37, a potent, selective, and orally bioavailable inhibitor of tyk2, exhibits a k i value of 1.6 nm. it is useful for researching inflammatory bowel diseases (ibd) [1].
Temsavir；化合物BMS626529BMS626529；BMS626529 (2024/9/8)
簡介：temsavir (bms626529) is a novel attachment inhibitor that targets hiv-1 gp120 and prevents its binding to cd4+ t cells.
ML 297；化合物ML297ML297；ML297 (2024/9/8)
簡介：ml 297 is a selective kir3.1/3.2 (girk1/2) channel activator (ic50 values are 160, 887 and 914 nm for girk1/2, girk1/4 and girk1/3 respectively). ml 297 exhibits no effect on girk2, girk2/3, kir2.1 and kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.
QX77；化合物QX77QX77 (2024/9/8)
簡介：qx77 is a chaperone-mediated autophagy (cma) activator.
SJ000291942；化合物SJ000291942SJ000291942 (2024/9/8)
簡介：sj000291942 is an activator of the canonical bone morphogenetic proteins (bmp) signaling pathway.
PKG drug G1；化合物PKG drug G1PKG drug G1 (2024/9/8)
簡介：pkg drug g1 targets pkg iα c42. pkg drug g1 can couple to vasodilation and blood pressure lowering by a c42 pkg iα-independent mechanism.
6,7-dimethoxy-N-(4-nitrophenyl)quinazoli；化合物T46606,7-dimethoxy-N-(4-nitrophenyl)quinazoli (2024/9/8)
簡介：6,7-dimethoxy-n-(4-nitrophenyl)quinazolin is used as a pharmaceutical intermediate.
ELN484228；化合物ELN484228ELN484228 (2024/9/8)
簡介：eln484228 is a α-synuclein blocker. α-synuclein is a key protein in parkinson’s disease.
MHP；化合物MHPMethyl caprooyl tyrosinate；Methyl caprooyl tyrosinate (2024/9/8)
簡介：mhp (methyl caprooyl tyrosinate) is an activator of sphingosine kinase (sphk1), and significantly stimulates camp mrna and protein production in kc.
WHI-P97 HCl 211555-05-4(free base)；化合物WHI-P97 HClWHI-P97 HCl 211555-05-4(free base) (2024/9/8)
簡介：whi-p97 hcl is a potent and selective jak-3 inhibitor. whi-p97 had an estimated ki value of 0.09 microm from modeling studies and a measured ic50 value of 2.5 microm in egfr kinase inhibition assays. whi-p97 effectively inhibited the in vitro invasiveness of egfr-positive human cancer cells in a concentration-dependent manner.
RAD51 Inhibitor B02；化合物B02B02；B02 (2024/9/8)
簡介：rad51 inhibitor b02 (b02) (b02) is an inhibitor of human rad51 with an ic50 of 27.4 μm.
Pipequaline哌夸林PK-8165|||哌夸林 (2024/9/8)
簡介：pipequaline (pk-8165) is an anticonflict & anticonvulsant quinoline derivative. it is an anxiolytic drug that was never marketed. it possesses a novel chemical structure that is not closely related to other drugs of this type. the drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.
(±)-Ibipinabant；化合物SLV319(±)-BMS6462|||SLV319|||(±)-SLV319；(±)-BMS6462|||SLV319|||(±)-SLV319 (2024/9/8)
簡介：(±)-ibipinabant ((±)-slv319) has been used in trials studying the treatment of obesity and obesity and type 2 diabetes.
C188-9；化合物C188-9TTI-101；TTI-101 (2024/9/8)
簡介：c188-9 (tti-101) is a stat3 inhibitor with an ic50 of 4-7 μm.
(S)-Monastrol化合物 (S)-MonastrolMonastrol (2024/9/8)
簡介：(s)-monastroll is a potent and cell-permeable inhibitor of the mitotic kinesin eg5.
最新產(chǎn)品 最新資訊 技術(shù)文章 公司動態(tài) 最新求購 分類瀏覽搜索標簽
Copyright 2009-2012 app17.com,all rights reserved ICP備案號：浙ICP備08105869號
MSN交談
會員服務(wù)咨詢：0571-85363692 客服熱線：0571-85363691 采購技術(shù)交流群號：187637045
