xanthanol;占噸氫醇NSC 4038;NSC 4038|||占噸氫醇 (2024/9/8)
簡(jiǎn)介:xanthanol(nsc 4038) is used to test the levels of urea in the bloodstream.
3-hydroxycephem;3-羥基頭孢3-hydroxycephem (2024/9/8)
簡(jiǎn)介:3-hydroxycephem 是各類(lèi)頭孢中間體。
4-Octyl itaconate4-辛基衣康酸4-辛基衣康酸|||衣康酸鹽 (2024/9/8)
簡(jiǎn)介:4-octyl itaconate is a cell-permeable derivative of itaconate, an anti-inflammatory metabolite. 4-octyl itaconate activates nrf2 via alkylation of keap1 and also inhibits phosphorylation of sting. 4-octyl itaconate is an anti-inflammatory metabolite.
Pentagastrin;五肽胃泌素ICI-50123;五肽胃泌素|||ICI-50123 (2024/9/8)
簡(jiǎn)介:pentagastrin (ici-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally, which can cause the secretion and synthesis of salivary proteins.
Tipranavir;替拉那韋PNU-140690;PNU-140690 (2024/9/8)
簡(jiǎn)介:tipranavir is a protease inhibitor that inhibits hiv-1 resistant to more than 1 protease inhibitor .tipranavir effectively inhibits hiv-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (pi) hiv-1 isolates (ic50 of 66-410 nm). tipranavir inhibits sars-cov-2 3clpro activity.
Cariprazine;卡利拉嗪RGH-188;卡利拉嗪|||RGH-188 (2024/9/8)
簡(jiǎn)介:cariprazine (rgh-188) is a novel antipsychotic drug candidate that exhibits high affinity for the d3 (ki=0.085 nm) and d2 (ki=0.49 nm) receptors, and moderate affinity for the 5-ht1a receptor (ki=2.6 nm).
Perospirone;哌羅匹隆Lullan;哌羅匹隆|||Lullan (2024/9/8)
簡(jiǎn)介:perospirone (lullan) is an antagonist of serotonin 5ht2a receptors and dopamine d2 receptors. it also displays affinity towards 5ht1a receptors as a partial agonist.
Chromium picolinate;吡啶甲酸鉻Chromium picolinate (2024/9/8)
簡(jiǎn)介:chromium picolinate causes dna damage and mutation. it is an activator of p38.
Sacubitril sodium;化合物 T4574LAHU377|||AHU-377|||LCZ696|||AHU 377;AHU377|||AHU-377|||LCZ696|||AHU 377 (2024/9/8)
簡(jiǎn)介:sacubitril is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. sacubitril is a prodrug that is activated to lbq657 by de-ethylation via esterases.
Sacubitril;沙庫(kù)必曲AHU 377|||AHU377|||AHU-377;AHU 377|||AHU377|||沙庫(kù)必曲|||AHU-377 (2024/9/8)
簡(jiǎn)介:sacubitril (ahu-377) is a potent nep inhibitor with an ic50 of 5 nm. sacubitril is a component of the heart failure medicine lcz696.
Cyclothiazide;環(huán)噻嗪Cyclothiazide (2024/9/8)
簡(jiǎn)介:cyclothiazide is a benzothiadiazide that acts as a potentiator of ampa receptorsthat potently inhibits ampa receptor desensitization, positively modulating its response to glutamic acid (ec50 = 3.8 m).
Desoximetasone;去羥米松Desoximetasonum|||Topicort|||Desoxymethasone|||Desoximetasona;去羥米松|||Desoximetaso (2024/9/8)
簡(jiǎn)介:desoximetasone (desoximetasona)(topicort), a topical corticosteroid, is employed for the alleviation of diverse skin conditions, including rashes.
Balsalazide;巴柳氮Balsalazido;巴柳氮|||Balsalazido (2024/9/8)
簡(jiǎn)介:balsalazide (balsalazido) is an anti-inflammatory compound used in the treatment of inflammatory bowel disease.
Pipobroman哌泊溴烷Vercyte|||A-8103|||Amedel|||哌泊溴烷 (2024/9/8)
簡(jiǎn)介:pipobroman (vercyte) is an anti-cancer drug that probably acts as an alkylating agent. pipobroman has well documented clinical activity in polycythemia vera (pv) and essential thrombocythemia (et). pipobroman allows, within 3 months, to attain a response in more than 90% of patients, without clinically relevant toxicities. the 10-years risk of thrombosis of patients treated with pipobroman is about 15%, the anti-proliferative activity of pipobroman on bone marrow megakaryocytes seems of particul
Lucanthone hydrochloride;化合物 T4569LLucanthone HCl;Lucanthone HCl (2024/9/8)
簡(jiǎn)介:lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.
Lucanthone;硫蒽酮Lucantona|||Lucanthonum;Lucantona|||Lucanthonum|||硫坎酮|||硫蒽酮 (2024/9/8)
簡(jiǎn)介:lucanthone (lucanthonum) is an inhibitor of apurinic endonuclease-1 (ape-1).
Dolasetron;多拉司瓊MDL-73147;MDL-73147|||多拉司瓊 (2024/9/8)
簡(jiǎn)介:dolasetron (mdl-73147)(mdl-73147) is a serotonin 5-ht3 receptor antagonist. dolasetron is used to treat nausea and vomiting following chemotherapy.
Sulfaphenazole磺胺苯吡唑Plisulfan|||Raziosulfa|||Depocid|||磺胺苯吡唑|||Depotsulfonamide (2024/9/8)
簡(jiǎn)介:sulfaphenazole (plisulfan) is an inhibitor of cyp2c9 (ki: 0.3 μm) that demonstrates at least 100-fold selectivity over other cyp450 isoforms (ki: 63/29 μm for cyp2c8/cyp2c18, respectively, and no activity at cyp1a1, cyp1a2, cyp3a4, cyp2c19). at 10 μm, sulfaphenazole has been shown to inhibit endothelium-derived hyperpolarizing factor synthase, a cyp450 isozyme in the porcine coronary artery homologous to cyp2c8/9 that generates reactive oxygen species in coronary endothelial cells and modulates
Lodoxamide;洛草氨酸Lodoxamidum;Lodoxamidum|||洛草氨酸 (2024/9/8)
簡(jiǎn)介:lodoxamide (lodoxamidum) is an antiallergic drug acting as a mast-cell stabilizer. it is effective in the treatment of asthma and allergic conjunctivitis.
Tafamidis;氯苯唑酸Fx-1006A;他發(fā)米帝司甲葡胺|||氯苯唑酸|||Fx-1006A (2024/9/8)
簡(jiǎn)介:tafamidis (fx-1006a) is a kinetic stabilizer of transthyretin (ttr) that prevents amyloidogenesis by wild-type and mutant ttrs. it binds to ttr with negative cooperativity (kd1: 3 nm; kd2: 278 nm) to stabilize the ttr dimer-dimer interface and inhibit tetrameric dissociation. tafamidis stabilizes wild-type and clinically significant v30m and v122i mutant ttr amyloidogenic homotetramers (ec50s: 2.7-3.2 μm) under fibril-promoting, denaturing, and physiological conditions in vitro. it stabilizes tt
Thonzylamine松齊拉敏neohetramine|||松齊拉敏 (2024/9/8)
簡(jiǎn)介:thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. it is available as combination products with clofedanol or phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhinitis) or other upper respiratory allergies.
Ramosetron hydrochloride;鹽酸雷莫司瓊YM 060|||YM-060|||YM060;鹽酸雷莫司瓊|||YM 060|||YM-060|||YM060 (2024/9/8)
簡(jiǎn)介:ramosetron hydrochloride (ym-060) is a serotonin 5-ht3 receptor antagonist. it is used to treat diarrhea-predominant irritable bowel syndrome and nausea.
Tiaprofenic acid;噻洛芬酸Tiaprofensaeure|||Acido tiaprofenico|||Surgam;Tiaprofensaeure|||噻洛芬酸|||Acido ti (2024/9/8)
簡(jiǎn)介:tiaprofenic acid (acido tiaprofenico) is a non-steroidal anti-inflammatory drug used to treat pain, especially arthritic pain.
Alprenolol tartrate, (S)-;化合物 T4560L2(S)-Alprenolol tartrate|||l-Alprenolol bitartrate;(S)-Alprenolo (2024/9/8)
簡(jiǎn)介:alprenolol tartrate, (s)- is an 5-ht1a antagonist.
Alprenolol hydrochloride, (S)-;化合物 T4560L1L-Alloprenalol hydrochloride;L-Alloprenalol hydrochloride (2024/9/8)
簡(jiǎn)介:alprenolol hydrochloride, (s)- is a nonselective β-blocker. it is also a serotonin 5ht1a receptor antagonist.
Isocarboxazid;異卡波肼Isocarboxazid (2024/9/8)
簡(jiǎn)介:isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. it is a monoamine oxidase inhibitor.[2] it is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders.
Trioxsalen三甲沙林三甲沙林|||Trimethylpsoralen|||Trioxysalen|||Trisoralen (2024/9/8)
簡(jiǎn)介:trioxsalen (trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with uv-a for phototherapy treatment of vitiligo and hand eczema. after photoactivation it creates interstrand cross-links in dna, which can cause programmed cell death.
Amylmetacresol;戊甲酚5-Methyl-2-Pentylphenol;戊甲酚|||5-Methyl-2-Pentylphenol (2024/9/8)
簡(jiǎn)介:amylmetacresol (5-methyl-2-pentylphenol) is used in the treatment of sore throat or ´acute sore throat´, pharyngitis, tonsillitis and laryngitis. as well as in the treatment of influenza a and sars-cov.
AG 1406;化合物AG 1406AG 1406 (2024/9/8)
簡(jiǎn)介:ag 1406 is a selective inhibitor of the receptor tyrosine kinase vegf receptor 2.
Procaine penicillin G;普魯卡因青霉素Duphapen|||Hydracillin|||Hostacillin;普魯卡因青霉素|||Duphapen|||Hydracillin|| (2024/9/8)
簡(jiǎn)介:procaine penicillin g (duphapen) (procaine benzylpenicillin) is an antibiotic useful for the treatment of a number of bacterial infections. specifically, it is used for syphilis, anthrax, mouth infections, pneumonia, diphtheria, cellulitis, and animal bites.