9月
Fursultiamine；呋喃硫胺Diteftin|||Judolor|||Alinamin F；Diteftin|||呋喃硫胺|||Judolor|||Alinamin F (2024/9/8)
簡介：fursultiamine (alinamin f) is a disulfide derivative of thiamine, or an allithiamine. it has potential uses in the treatment of vitamin b1 deficiency.
Acrivastine；阿伐斯汀Acrivastin|||BW825C|||Semprex；Acrivastin|||阿伐斯汀|||BW825C|||Semprex (2024/9/8)
簡介：acrivastine (acrivastin) is a short-acting histamine 1 receptor antagonist.
Ajmaline hydrochloride；化合物 T4550LAjmaline hydrochloride (2024/9/8)
簡介：ajmaline hydrochloride is an alkaloid found in the root of rauwolfia serpentina, and other plant sources. it is a class of ia antiarrhythmic agent that apparently works by changing the shape and threshold of cardiac action potentials.
Ajmaline阿義馬林Cardiorythmine|||Raugalline|||阿義嗎啉|||阿義馬林|||Tachmalin|||(+)-Ajmaline (2024/9/8)
簡介：ajmaline (cardiorythmine) is a class ia anti-arrhythmic compound that is widely used for the diagnosis of brugada syndrome and the acute treatment of atrial or ventricular tachycardia. ajmaline inhibits cardiac kv1.5 and kv4.3 channels at therapeutic concentrations.
Procaterol hydrochloride；鹽酸丙卡特羅Procaterol hydrochloride (2024/9/8)
簡介：short-acting β2-adrenergic receptor agonist used to treat asthma.
Grazoprevir；化合物GrazoprevirMK-5172；MK-5172 (2024/9/8)
簡介：grazoprevir (mk-5172) is a selective inhibitor of hepatitis c virus ns3/4a protease with broad activity across genotypes and resistant variants, with ki of 0.01 nm (gt1a), 0.08 nm (gt2a), 0.90 nm (gt3a), 0.01 nm (gt1b), 0.15 nm (gt2b), respectively.
Dinoprost tromethamine salt；地諾前列素氨丁三醇Dinoprost Tromethamine|||Zinoprost|||Prostin F2 alpha|||PGF2α T (2024/9/8)
簡介：dinoprost tromethamine salt (pgf2α tham) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
Propacetamol Hydrochloride；鹽酸丙帕他莫Propacetamol HCL；鹽酸丙帕他莫|||Propacetamol HCL (2024/9/8)
簡介：propacetamol hydrochloride (propacetamol hcl) is a prodrug of paracetamol (acetaminophen) with improved water solubility. propacetamol hydrochloride is an analgesic drug delivered by iv when the oral application of nsaid is not appropriate or contradicted.
Elbasvir；化合物ElbasvirMK-8742；MK-8742 (2024/9/8)
簡介：elbasvir (mk-8742) is an inhibitor of nonstructural protein 5a (ns5a) of hepatitis c virus (hcv) being developed as a component of treatment regimens for chronic hcv infection.
Telithromycin；泰利霉素HMR3647|||Ketek|||RU66647；HMR3647|||泰利霉素|||Ketek|||RU66647 (2024/9/8)
簡介：telithromycin (hmr3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. antibacterial telithromycin prevents bacteria from growing, by interfering with their protein synthesis. telithromycin binds to the subunit 50s of the bacterial ribosome, and blocks the progression of the growing polypeptide chain. telithromycin has over 10 times higher affinity to the subunit 50s than erythromycin. in addition, telithromycin strongly bind simultaneously to two do
Clonixin；氯尼辛Clonixic acid；Clonixic acid|||氯尼辛 (2024/9/8)
簡介：clonixin (clonixic acid) is a non-steroidal anti-inflammatory drug (nsaid) with analgesic properties. this compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.
ML-18；化合物ML 18ML-18 (2024/9/8)
簡介：ml-18 is a non-peptide bombesin receptor subtype-3 (brs-3) antagonist with an ic50 of 4.8 μm.
Nicainoprol；尼卡普醇RU-42924；尼卡普醇|||RU-42924 (2024/9/8)
簡介：nicainoprol (ru-42924) is a fast-sodium-channel blocking drug. nicainoprol is a potent antiarrhythmic agent.
palovarotene；帕羅伐汀Ro 3300074|||R 667；Ro 3300074|||R 667|||帕羅伐汀 (2024/9/8)
簡介：palovarotene (ro 3300074) is an agonist of nuclear retinoic acid receptor γ (rar-γ).
Cholic acid sodium；膽酸鈉SodiumCholate；膽酸鈉|||[膽酸鈉]|||SodiumCholate (2024/9/8)
簡介：cholic acid sodium (sodiumcholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (hiv)-1] activity.
Pleconaril；普可那利VP 63843|||Win 63843|||Picovir；VP 63843|||Win 63843|||Picovir|||普可那利 (2024/9/8)
簡介：pleconaril (vp 63843) is a capsid inhibitor used previously to treat enterovirus infections. pleconaril is effective in inhibiting replication (ic50: 50 nm).
Etomoxir；乙莫克舍(R)-(+)-Etomoxir；(R)-(+)-Etomoxir (2024/9/8)
簡介：etomoxir is a carnitine palmitoyltransferase 1a (cpt-1a) inhibitor that inhibits fatty acid oxidation by inhibiting cpt-1a and inhibits palmitate oxidation in humans, rats, and guinea pigs. etomoxir has an inhibitory effect on adenine nucleotide translocase and can inhibit macrophage polarization by disrupting coa homeostasis.
Etomoxir sodium salt；(R)-(+)-乙莫克舍鈉鹽(R)-Etomoxir sodium salt|||Na salt|||Etomoxir；(R)-(+)-乙莫克舍鈉鹽|||(R (2024/9/8)
簡介：etomoxir sodium salt ((r)-etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (cpt-1a) inhibitor that blocks fatty acid synthesis. etomoxir sodium salt has antitumor activity.
BMS-309403；化合物BMS-309403Inhibitor|||BMS309403|||selective|||BMS 309403|||BMS-309403|||oral|||Fatty a (2024/9/8)
簡介：bms-309403 is an effective, selective and cell-permeable inhibitor of fatty acid binding protein 4 (fabp4) with a ki of less than 2 nm.
Serlopitant；化合物 T4533Serlopitant (2024/9/8)
簡介：serlopitant is a selective antagonist of neurokinin-1 (nk-1) receptor.
Linrodostat mesylate；化合物 T4532LONO-7701|||BMS-986205|||ONO 7701|||BMS986205|||BMS 986205；ONO-7701||| (2024/9/8)
簡介：linrodostat (bms-986205, ono-7701, and f001287) is a selective and orally active ido1 inhibitor with potential immunomodulating and antineoplastic activities. by inhibiting ido1 and reducing kynurenine in tumor cells, bms-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory t cells (tregs).
GSK2200150A；化合物GSK2200150AGSK2200150A (2024/9/8)
簡介：gsk2200150a is an anti-tuberculosis (tb) agent identified by high-throughput screening (hts) campaign.
KN-92；化合物 T4530LK92|||KN-92 free base|||K 92；K92|||KN-92 free base|||K 92 (2024/9/8)
簡介：kn-92 is an inactive analog of the cam kinase ii inhibitor kn 93.
KN-92 phosphate；KN-92 磷酸鹽KN92-H3PO4；KN-92 磷酸鹽|||KN92-H3PO4 (2024/9/8)
簡介：kn-92 phosphate (kn92-h3po4) is an inactive derivative of kn-93. kn-93 is a selective inhibitor of ca2+/calmodulin-dependent kinase ii (camkii), competitively blocking cam binding to the kinase (ki = 370 nm).
ASP-9521；化合物ASP9521ASP9521；ASP9521 (2024/9/8)
簡介：asp-9521 is an effective, specific and orally available akr1c3 inhibitor (ic50: 11 nm, for human).
Tyrphostin AG 528；化合物Tyrphostin AG 528Tyrphostin B66|||AG 528；Tyrphostin B66|||AG 528 (2024/9/8)
簡介：tyrphostin ag 528 (tyrphostin b66) is an inhibitor of egfr (ic50: 4.9 μm) and erbb2 (ic50: 2.1 μm).
Seclidemstat化合物SeclidemstatSP-2577 (2024/9/8)
簡介：seclidemstat (sp-2577) is an effective lsd1 inhibitor, with a mean ic50 of 127 nm.
Piperoxan hydrochloride；鹽酸哌羅克生dl-Piperoxan hydrochloride|||Benodaine hydrochloride；dl-Piperoxan hydr (2024/9/8)
簡介：piperoxan hydrochloride (benodaine hydrochloride) is an α2 adrenoceptor antagonist. piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered.
Citraconic acid；檸康酸2-Methylmaleic Acid|||Cis-Methylbutenedioic Acid；2-Methylmaleic Acid|||檸康酸|||Cis- (2024/9/8)
簡介：citraconic acid (2-methylmaleic acid) is a dicarboxylic acid consisting of maleic acid having a methyl substituent at the 2-position.
SBC-110736；化合物SBC-110736SBC110736；SBC110736 (2024/9/8)
簡介：sbc-110736 is a proprotein convertase subtilisin kexin type 9 (pcsk9) inhibitor
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