9月
Daucosterol；胡蘿卜苷Alexandrin|||Sitogluside|||β-Sitosterol β-D-glucoside|||Eleutheroside A；Alexandrin|| (2024/9/8)
簡(jiǎn)介：daucosterol (sitogluside) has proliferation-enhancing activity, may be involved in the igf1-akt pathway. daucosterol(β-sitosterol β-d-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to igf1-like activity, could be potentially developed as a medicine for ischemic stroke treatment.
PFM39；化合物 PFM39PFM39 (2024/9/8)
簡(jiǎn)介：pfm39 is a selective mre11 nucleic acid exonuclease inhibitor and mirin analog that prolongs mitosis.pfm39 inhibits hr and alleviates repair defects caused by exo1/blm depletion.
6-Acetyldepheline；6-Acetyldepheline6-Acetyldepheline (2024/9/8)
簡(jiǎn)介：6-acetyldepheline, a natural alkaloid, can be isolated from delphinium tatsienense.
MPC-0767；MPC-0767MPC-0767 (2024/9/8)
簡(jiǎn)介：mpc-0767, a potent, selective, and orally active hsp90 inhibitor, is the l-alanine ester prodrug of mpc-3100, exhibiting enhanced chemical stability.
MS-PEG1-THP；MS-PEG1-THPMS-PEG1-THP；MS-PEG1-THP (2024/9/8)
簡(jiǎn)介：ms-peg1-thp is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
2-Bromo-6-nitrophenol；2-Bromo-6-nitrophenol2-Bromo-6-nitrophenol (2024/9/8)
簡(jiǎn)介：2-bromo-6-nitrophenol undergoes transformation into 2-bromo-6-aminophenol, which is subsequently converted to n-acetyl-2-bromo-6-aminophenol.
Thiol-C9-PEG7；Thiol-C9-PEG7Thiol-C9-PEG7；Thiol-C9-PEG7 (2024/9/8)
簡(jiǎn)介：thiol-c9-peg7 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Thiol-C9-PEG5；Thiol-C9-PEG5Thiol-C9-PEG5；Thiol-C9-PEG5 (2024/9/8)
簡(jiǎn)介：thiol-c9-peg5 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Thiol-C9-PEG4；Thiol-C9-PEG4Thiol-C9-PEG4；Thiol-C9-PEG4 (2024/9/8)
簡(jiǎn)介：thiol-c9-peg4 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Cyasterone杯莧甾酮杯莧甾酮|||Cyasteron (2024/9/8)
簡(jiǎn)介：cyasterone (cyasteron), a natural egfr inhibitor, can inhibit the growth of a549 and mgc823 cells, via regulating egfr signaling pathway, it may be a promising anti-cancer agent. cyasterone has antifeeding activity.
Piperafizine A；化合物Piperafizine APiperafizine A (2024/9/8)
簡(jiǎn)介：piperafizine a is isolated from streptoverticillium aspergilloides and potentiates vincristine antitumor potency.
Cathayanon H；Cathayanon HCathayanon H (2024/9/8)
簡(jiǎn)介：cathayanon h, a compound derived from the paper mulberry tree, exhibits cytotoxicity against human ovarian carcinoma cells.
[Tyr(P)4]u00A0Angiotensinu00A0II；[Tyr(P)4] Angiotensin II[Tyr(P)4]u00A0Angiotensinu00A0II (2024/9/8)
簡(jiǎn)介：[tyr(p)4] angiotensin ii is a peptide that exerts a multitude of effects on vascular smooth muscle. these effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.
Rp-8-CPT-cAMPS；Rp-8-CPT-cAMPSRp-8-CPT-cAMPS (2024/9/8)
簡(jiǎn)介：rp-8-cpt-camps is a powerful and competitive antagonist of camp-induced activation of camp-dependent protein kinase (pka) i and ii. acting as a potent camp analog, rp-8-cpt-camps exhibits a preference for site a of ri over site a of rii. additionally, it favors site b of rii over site b of ri. this compound effectively inhibits camp-dependent pka activation and demonstrates selectivity in binding to specific sites within the protein kinase.
2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose；2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranos (2024/9/8)
簡(jiǎn)介：2-acetamido-2,4-dideoxy-4-fluoro-α-d-glucopyranose (compound 13) functions as a potent hepatic glycosaminoglycan biosynthesis inhibitor.
Sp-8-CPT-cAMPS；Sp-8-CPT-cAMPSSp-8-CPT-cAMPS (2024/9/8)
簡(jiǎn)介：sp-8-cpt-camps is a powerful and specific camp analog that activates camp-dependent protein kinase a (pka i and pka ii) selectively and effectively. it exhibits a 153-fold preference for site a of ri over site a of rii, and a 59-fold preference for site b of rii over site b of ri.
TRC160334TRC160334TRC160334 (2024/9/8)
簡(jiǎn)介：trc160334 is a hydroxylase inhibitor of hypoxia-inducible factor (hif). it is employed in research about ischemia/reperfusion injury.
Fabesetron法貝司瓊法貝司瓊|||FK1052 free base (2024/9/8)
簡(jiǎn)介：fabesetron (fk1052) is an orally active compound that acts as a dual antagonist, targeting both the 5-ht3 and 5-ht4 receptors. it exhibits efficacy in studying emesis induced by cancer chemotherapy, showing potential for managing both acute and delayed symptoms.
Benzyl-PEG6-Ots；Benzyl-PEG6-OtsBenzyl-PEG6-Ots；Benzyl-PEG6-Ots (2024/9/8)
簡(jiǎn)介：benzyl-peg6-ots is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Benzyl-PEG5-Ots；Benzyl-PEG5-OtsBenzyl-PEG5-Ots；Benzyl-PEG5-Ots (2024/9/8)
簡(jiǎn)介：benzyl-peg5-ots is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Skimmin；茵芋苷Skimmine；茵芋苷|||Skimmine (2024/9/8)
簡(jiǎn)介：skimmin (skimmine) has anti-inflammatory activity, can significantly improve renal function and suppress the igg deposition as well as the development of glomerular lesions in a rat model of membranous glomerulonephritis.
Propargyl-PEG5-Br；Propargyl-PEG5-BrPropargyl-PEG5-Br；Propargyl-PEG5-Br (2024/9/8)
簡(jiǎn)介：propargyl-peg5-br is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG2-bromide；Propargyl-PEG2-bromidePropargyl-PEG2-bromide；Propargyl-PEG2-bromide (2024/9/8)
簡(jiǎn)介：propargyl-peg2-bromide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Influenza Matrix Protein (61-72)；Influenza Matrix Protein (61-72)Influenza Matrix Protein (61-72) (2024/9/8)
簡(jiǎn)介：influenza matrix protein (61-72) is a peptide derived from the matrix protein of influenza viruses and encompasses amino acids 61-72. this specific epitope, influenza matrix protein (61-72), has the ability to elicit a cd4+ t-cell response.
Melarsomine；美拉索明Melarsomine (2024/9/8)
簡(jiǎn)介：melarsomine, a trivalent arsenical compound, is employed as an adulticide for canine heartworm disease and other helminth infections. it has significant utility in the research of these conditions.
C12-Sphingosine；C12-SphingosineC12-Sphingosine；C12-Sphingosine (2024/9/8)
簡(jiǎn)介：c12-sphingosine is a short-chain homologue of sphingosine. it effectively inhibits the activity of serine palmitoyltransferase in primary cultured cerebellar cells.
AKR1C3-IN-4；化合物AKR1C3-IN-4AKR1C3-IN-4；AKR1C3-IN-4 (2024/9/8)
簡(jiǎn)介：akr1c3-in-4 is a potent and selective inhibitor of aldo-keto reductase 1c3 (akr1c3) with an ic50 of 0.56 μm. akr1c3-in-4 has the potential for castrate resistant prostate cancer (crpc) research.
SCD1 inhibitor-3；化合物SCD1 inhibitor-3SCD1-IN-3|||SCD1 inhibitor-3|||SCD1 inhibitor 17a；SCD1-IN-3|||SC (2024/9/8)
簡(jiǎn)介：scd1 inhibitor-3 (ml-270) is a highly effective and orally available compound that inhibits scd1 with remarkable safety. scd1 inhibitor-3 demonstrates strong potential for research in metabolic diseases, including obesity, type ii diabetes, and dyslipidemia, as well as various skin conditions like acne and cancer.
Lys-Nε-SPDB-DM4；Lys-Nε-SPDB-DM4Lys-Nε-SPDB-DM4；Lys-Nε-SPDB-DM4 (2024/9/8)
簡(jiǎn)介：lys-nε-spdb-dm4 is a drug-linker conjugate that combines the tubulin inhibitor dm4 with the linker lys-nε-spdb, facilitating the creation of an antibody-drug conjugate (adc).
P-SCN-Bn-DOTA；化合物P-SCN-Bn-DOTAP-SCN-Bn-DOTA (2024/9/8)
簡(jiǎn)介：p-scn-bn-dota is a chelator that simultaneously chelates radionuclides and connects monoclonal antibodies. it can be used as a tracer for radio-guided surgery and can be used for radio-immunoassay studies of tumors.
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